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應用
氨磷汀可以使用生长抑素类似物减轻辐射损伤并减少吸收的肾脏辐射剂量,从而在PRRT期间提供肾脏保护。氨磷汀可补救辐射对鼠下颌骨矿化能力的退化作用。
生化/生理作用
辐射防护剂。选择性地保护正常组织免受抗肿瘤放射疗法的破坏作用。选择性归因于正常组织的优先摄取以及随后对2-(3-氨基丙基)氨基乙硫醇的代谢活化。
訊號詞
Warning
危險聲明
危險分類
Acute Tox. 4 Oral
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
個人防護裝備
dust mask type N95 (US), Eyeshields, Gloves
Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 21(1), 357-364 (2012-10-12)
The aim of this study was to review the available literature from 1966 until December 31, 2010 and define clinical practice guidelines for the use of amifostine for the prevention and treatment of oral mucositis in cancer patients. A systematic
Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale, 41(5), 309-315 (2012-10-25)
The effectiveness of amifostine in the prevention of cisplatin ototoxicity remains controversial. The objective of this meta-analysis was to determine whether amifostine is successful in preventing ototoxicity secondary to cisplatin chemotherapy. Meta-analysis. We conducted a systematic review of all randomized
Hematology/oncology and stem cell therapy, 5(3), 152-157 (2012-10-26)
We report the 8-year follow-up of 34 patients aged ≥69 years old with NHL included in a phase IIb open-label randomized parallel groups study to evaluate the effectiveness of amifostine in preventing the toxicity of cyclophosphamide, doxorubicin, vincristine and prednisone
Journal of cancer research and therapeutics, 8(2), 260-265 (2012-07-31)
The aim of the study was to compare the protective efficacy of l-carnitine (LC) to amifostine on radiation-induced acute small intestine damage. Thirty, 4-week-old Wistar albino rats were randomly assigned to four groups - Group 1: control (CONT, n =
International journal of radiation oncology, biology, physics, 85(1), e7-13 (2012-10-09)
Postmastectomy radiation therapy (PMRT) provides major local control and survival benefits. More aggressive radiation therapy schemes may, however, be necessary in specific subgroups, provided they are safely administered. We report the tolerance and efficacy of a highly accelerated and hypofractionated
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