A3355

ATC0175

≥98% (HPLC), solid

• 别名: N-(cis-4-{[4-(Dimethylamino)quinazolin-2-yl]amino}cyclohexyl)-3,4-difluorobenzamide HCl
• 经验公式（希尔记法）: C₂₃H₂₆ClF₂N₅O
• CAS号: 510733-97-8
• 分子量: 461.94
• MDL號碼: MFCD08276913
• 分類程式碼代碼: 51111800
• PubChem物質ID: 24724389
• NACRES: NA.77

属性

• 化驗: ≥98% (HPLC)
• 形狀: solid
• 溶解度: DMSO: soluble 5 mg/mL; H₂O: insoluble
• 儲存溫度: 2-8°C
• SMILES 字串: Cl[H].CN(C)c1nc(N[C@@H]2CC[C@@H](CC2)NC(=O)c3ccc(F)c(F)c3)nc4ccccc14
• InChI: 1S/C23H25F2N5O.ClH/c1-30(2)21-17-5-3-4-6-20(17)28-23(29-21)27-16-10-8-15(9-11-16)26-22(31)14-7-12-18(24)19(25)13-14;/h3-7,12-13,15-16H,8-11H2,1-2H3,(H,26,31)(H,27,28,29);1H/t15-,16+;
• InChI 密鑰: HUUPKFUYSQNNLO-FAESNJTISA-N

说明

生化／生理作用

ATC0175 is a non-peptide, orally active melanin-concentrating hormone receptor 1 (MCHR1) antagonist.

Non-peptide, orally active melanin-concentrating hormone receptor 1 (MCHR1) antagonist.

特點和優勢

This compound is featured on the Melanin-Concentrating Hormone Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

安全信息

• 象形圖: GHS07
• 訊號詞: Warning
• 危險聲明: H315,H319,H335,H413
• 防範說明: P273 - P302 + P352 - P305 + P351 + P338
• 危險分類: Aquatic Chronic 4 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• 標靶器官: Respiratory system
• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable
• 個人防護裝備: dust mask type N95 (US), Eyeshields, Gloves