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Merck

A3013

Sigma-Aldrich

腺苷 2′(3′)-单磷酸混合异构体

别名:

酵母腺苷酸

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About This Item

经验公式(希尔记法):
C10H14N5O7P
CAS号:
分子量:
347.22
EC號碼:
MDL號碼:
分類程式碼代碼:
41106305
PubChem物質ID:
NACRES:
NA.51

生物源

synthetic

化驗

≥45% (Adenosine-3′-monophosphate, HPLC)
≥97% (Total Adenosine-3′-monophosphate; Adenosine-2′-monophosphate, HPLC)
10-55% ( Adenosine-2′-monophosphate, HPLC)

形狀

powder

溶解度

1 M NH4OH: 50 mg/mL, clear, colorless

儲存溫度

−20°C

SMILES 字串

Nc1ncnc2n(cnc12)[C@@H]3O[C@H](CO)[C@@H](OP(O)(O)=O)[C@H]3O.Nc4ncnc5n(cnc45)[C@@H]6O[C@H](CO)[C@@H](O)[C@H]6OP(O)(O)=O

InChI

1S/2C10H14N5O7P/c11-8-5-9(13-2-12-8)15(3-14-5)10-6(17)7(4(1-16)21-10)22-23(18,19)20;11-8-5-9(13-2-12-8)15(3-14-5)10-7(22-23(18,19)20)6(17)4(1-16)21-10/h2*2-4,6-7,10,16-17H,1H2,(H2,11,12,13)(H2,18,19,20)/t2*4-,6-,7-,10-/m11/s1

InChI 密鑰

UQRXDDDXDPEXNS-VQFZJOCSSA-N

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相关类别

一般說明

3′-单磷酸腺苷(3′-AMP)和2′-单磷酸腺苷(2′-AMP)是由金属依赖性磷酸二酯酶家族水解2′,3′-cAMP产生的代谢产物。2′-AMP和3′-AMP通过A2B受体抑制肾小球前血管平滑肌细胞和肾小球系膜细胞的增殖。

應用

腺苷2′(3′)-单磷酸盐混合异构体被用作分离和分离的标准物定量嘌呤(腺嘌呤和鸟嘌呤)和腺嘌呤核糖核苷单磷酸盐(2’-AMP 和 3’-AMP)通过等温高性能液体色谱法 (HPLC)。它也被用来筛选多个糖结合 ATPase A (MsbA) 转运蛋白。

聯結

不要与腺苷 2′:3′-环一磷酸混淆

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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G S Padiyar et al.
Journal of biomolecular structure & dynamics, 15(4), 803-821 (1998-03-26)
Crystal structures of lithium, sodium, potassium, calcium and magnesium salts of adenosine 2'-monophosphate (2'-AMP) have been obtained at atomic resolution by X-ray crystallographic methods. 2'-AMP.Li belongs to the monoclinic space group P2(1) with a = 7.472(3)A, b = 26.853(6) A
Alexander F Yakunin et al.
The Journal of biological chemistry, 279(35), 36819-36827 (2004-06-24)
In all mature tRNAs, the 3'-terminal CCA sequence is synthesized or repaired by a template-independent nucleotidyltransferase (ATP(CTP):tRNA nucleotidyltransferase; EC 2.7.7.25). The Escherichia coli enzyme comprises two domains: an N-terminal domain containing the nucleotidyltransferase activity and an uncharacterized C-terminal HD domain.
G S Padiyar et al.
Journal of biomolecular structure & dynamics, 15(4), 793-802 (1998-03-26)
This paper reports the crystal structures of free acid and ammonium salt of adenosine 2'-monophosphate (2'-AMP). 2'-AMP crystallizes in the hexagonal space group P6(5)22 with a = 9.530(3) A, c = 73.422(2) A, and Z= 12. 2'-AMP.NH4 crystallizes in the
Maria V Papadopoulou et al.
Oncology research, 14(1), 21-29 (2003-10-14)
The enzymatic cell-free metabolism of the novel hypoxia-selective cytotoxin 4-[3-(2-nitro-1-imidazolyl)-propylamino]-7-chloroquinoline hydrochloride (NLCQ-1) was investigated under hypoxic or aerobic conditions in the presence of purified reductive enzymes or isolated rat liver microsomes by monitoring the parent compound with HPLC-UV analysis. Enzymatic
Periprocedural type IVa myocardial infarction and the importance of platelet inhibition.
Anoop S V Shah et al.
Heart (British Cardiac Society), 99(17), 1225-1226 (2013-04-18)

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