生物源
Saccharomyces cerevisiae
化驗
≥98.0% (HPLC)
形狀
powder
雜質
≤5% solvent
≤8.5% water
溶解度
H2O: 50 mg/mL, clear
儲存溫度
−20°C
SMILES 字串
[Na+].[Na+].OC[C@H]1O[C@H](OP([O-])(=O)OP([O-])(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N3C=CC(=O)NC3=O)[C@H](O)[C@@H](O)[C@@H]1O
InChI
1S/C15H24N2O17P2.2Na/c18-3-5-8(20)10(22)12(24)14(32-5)33-36(28,29)34-35(26,27)30-4-6-9(21)11(23)13(31-6)17-2-1-7(19)16-15(17)25;;/h1-2,5-6,8-14,18,20-24H,3-4H2,(H,26,27)(H,28,29)(H,16,19,25);;/q;2*+1/p-2/t5-,6-,8-,9-,10+,11-,12-,13-,14-;;/m1../s1
InChI 密鑰
PKJQEQVCYGYYMM-QBNUFUENSA-L
一般說明
5′-二磷酸尿苷葡萄糖二钠盐是由尿嘧啶碱基、核糖和2个磷酸基团组成的核苷酸糖。
應用
UDP-葡萄糖已用于：
- 作为糖苷化合物的酶促生产底物，并用于它们的液相色谱-质谱检测。
- 作为底物用于人CMP-Sia转运蛋白的底物筛选和吸附亲和力测定。
生化／生理作用
UDP-葡萄糖是UDP-半乳糖和UDP-葡糖醛酸的前体。在动物和某些微生物中，它还用于含葡萄糖分子的生物合成，例如寡糖、多糖、糖蛋白和糖脂。多个研究表明，除了经典的代谢作用外，UDP-葡萄糖可能是植物中的信号分子。5′二磷酸尿苷葡萄糖可作为激动剂作用于G蛋白偶联受体(GPCR)嘌呤受体P2Y14，参与树突状细胞和胶质细胞的激活。也可通过激活G蛋白偶联受体17(GPR17)诱导少突胶质细胞分化。
其他說明
促进甲烷杆菌无细胞提取液中甲基辅酶 M 的降解
取代透過
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
Eyeshields, Gloves, type N95 (US)
Nan Li et al.
Carbohydrate research, 446-447, 61-67 (2017-05-22)
Corylifol A, a member of the isoflavone subclass of isoflavonoids, has long been considered to have various biological activities. Here, we sought to synthesize corylifol A glucosides by the in vitro glucosylation reaction using the UDP-glycosyltransferase YjiC from Bacillus licheniformis DSM
Sen Yin et al.
Plant physiology and biochemistry : PPB, 109, 536-548 (2016-11-12)
UDP-L-rhamnose (UDP-Rha) is an important sugar donor for the synthesis of rhamnose-containing compounds in plants. However, only a few enzymes and their encoding genes involved in UDP-Rha biosynthesis are available in plants. Here, two genes encoding rhamnose synthase (RhS) and
Jo M Vanoevelen et al.
Journal of inherited metabolic disease, 41(1), 117-127 (2017-09-16)
Classic galactosemia is a genetic disorder of galactose metabolism, caused by severe deficiency of galactose-1-phosphate uridylyltransferase (GALT) enzyme activity due to mutations of the GALT gene. Its pathogenesis is still not fully elucidated, and a therapy that prevents chronic impairments
Ayako Ikegami et al.
Planta, 230(4), 841-855 (2009-07-31)
Fruits of persimmon (Diospyros kaki Thunb.) accumulate large amounts of proanthocyanidins (PAs) in the early stages of development. Astringent (A)-type fruits remain rich in soluble PAs even after they reach full-mature stage, whereas non-astringent (NA)-type fruits lose these compounds before
Alexander Gutmann et al.
Organic & biomolecular chemistry, 15(37), 7917-7924 (2017-09-14)
Various bioactive natural products, like the aminocoumarin antibiotics novobiocin and coumermycin, exhibit an aromatic C-methyl group adjacent to a glycosylated phenolic hydroxyl group. Therefore, tailoring of basic phenolic scaffolds to contain the intricate C-methyl/O-glycosyl motif is of high interest for
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