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82934

Sigma-Aldrich

7-Hydroxycitronellal

Odorant used in allergy studies

别名:

7-Hydroxy-3,7-dimethyloctanal, Citronellal hydrate

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200 μL
£490.00

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200 μL
£490.00

About This Item

经验公式（希尔记法）:
C10H20O2
CAS号:
107-75-5
分子量:
172.26
EC號碼:
203-518-7
MDL號碼:
MFCD00014681
分類程式碼代碼:
12352200
PubChem物質ID:
57652938
NACRES:
NA.52

£490.00

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如需订购该产品，请通过联系信息 联系默克当地经销商。

等級

for molecular biology

品質等級

100

化驗

≥95.0% (GC)

形狀

powder

密度

0.92 g/mL at 20 °C (lit.)

儲存溫度

room temp

SMILES 字串

[H]C(CC(C)CCCC(O)(C)C)=O

InChI

1S/C10H20O2/c1-9(6-8-11)5-4-7-10(2,3)12/h8-9,12H,4-7H2,1-3H3

InChI 密鑰

WPFVBOQKRVRMJB-UHFFFAOYSA-N

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Anti-Progerin antibody, Mouse monoclonal clone 13A4, purified from hybridoma cell culture

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Anti-Progerin antibody, Mouse monoclonal

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

biological source

mouse

biological source

mouse

biological source

mouse

biological source

mouse

Gene Information

human ... ASF1A(25842)

Gene Information

human ... ATG5(9474)
mouse ... Atg5(11793)
rat ... Atg5(365601)

Gene Information

human ... MDC1(9656)

Gene Information

human ... LMNA(4000)

antibody form

purified from hybridoma cell culture

antibody form

purified immunoglobulin

antibody form

purified from hybridoma cell culture

antibody form

purified from hybridoma cell culture

species reactivity

mouse, human

species reactivity

human, mouse, rat

species reactivity

monkey, human

species reactivity

human

一般說明

7-Hydroxycitronellal is fragrant sensitizer added frequently to deodorants and perfumes. It is one of the allergens responsible for axillary dermatitis.[1]

應用

Suitable for
  • contact sensitization studies to identify allergens present in cosmetic preparations
  • elucidation of molecular pathways related to allergic reactions
  • analytical standard

象形圖

Exclamation mark
GHS07

訊號詞

Warning

危險聲明

H315,H317,H319

危險分類

Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1

儲存類別代碼

10 - Combustible liquids

水污染物質分類（WGK）

WGK 1

閃點（°F）

Not applicable

閃點（°C）

Not applicable

個人防護裝備

Eyeshields, Gloves, type ABEK (EN14387) respirator filter

    • 历史批次信息供参考:

    分析证书(COA)

    Lot/Batch Number
    BCCG7280
    BCCG1914
    BCCD2891
    BCCB7386
    BCBS8648V

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    Nadège Ade et al.
    Toxicological sciences : an official journal of the Society of Toxicology, 107(2), 451-460 (2008-11-27)
    Electrophilicity is one of the most common features of skin contact sensitizers and is necessary for protein haptenation. The Keap1 (Kelch-like ECH-associated protein 1)/Nrf2 -signaling pathway is dedicated to the detection of electrophilic stress in cells leading to the upregulation
    Clarissa D Villarama et al.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 42(11), 1719-1725 (2004-09-08)
    The clinical relevance of patch test reactions is often difficult to determine. Use tests have been developed to further evaluate the significance of patch test results. We review studies that have defined correlations between the threshold concentrations at patch testing
    S Heydorn et al.
    Contact dermatitis, 48(6), 324-330 (2003-10-09)
    Recently, we showed that 10 x 2% of consecutively patch-tested hand eczema patients had a positive patch test to a selection of fragrances containing fragrances relevant to hand exposure. In this study, we used repeated skin exposure to a patch
    Susan P Felter et al.
    Regulatory toxicology and pharmacology : RTP, 37(1), 1-10 (2003-03-29)
    The National Academy of Science (NAS) risk assessment paradigm has been widely accepted as a framework for estimating risk from exposure to environmental chemicals (NAS, 1983). Within this framework, quantitative risk assessments (QRAs) serve as the cornerstone of health-based exposure
    M Krasteva et al.
    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 26(5), 563-570 (1996-05-01)
    The need to develop predictive tests which could identify potential allergens has been recognized for many years. There is as yet no accepted in vitro method for the assessment of contact sensitizers. We have tested the ability of a range
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