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Merck

78544

Sigma-Aldrich

葡萄糖四糖

≥99.0% (TLC)

别名:

Glcα1-6Glcα1-4Glcα1-4Glc

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About This Item

经验公式(希尔记法):
C24H42O21
CAS号:
分子量:
666.58
MDL號碼:
分類程式碼代碼:
12352201
PubChem物質ID:
NACRES:
NA.28

品質等級

化驗

≥99.0% (TLC)

形狀

powder

顏色

white

適合性

corresponds for LC-MS

儲存溫度

room temp

SMILES 字串

OC[C@H]1O[C@H](OC[C@H]2O[C@H](O[C@H]3[C@H](O)[C@@H](O)[C@H](O[C@@H]3CO)O[C@H]4[C@H](O)[C@@H](O)C(O)O[C@@H]4CO)[C@H](O)[C@@H](O)[C@@H]2O)[C@H](O)[C@@H](O)[C@@H]1O

InChI

1S/C24H42O21/c25-1-5-9(28)11(30)16(35)22(41-5)39-4-8-10(29)12(31)17(36)23(43-8)45-20-7(3-27)42-24(18(37)14(20)33)44-19-6(2-26)40-21(38)15(34)13(19)32/h5-38H,1-4H2/t5-,6-,7-,8-,9-,10-,11+,12+,13-,14-,15-,16-,17-,18-,19-,20-,21?,22+,23-,24-/m1/s1

InChI 密鑰

FPBCRLIOSBQLHS-QVTSYAGHSA-N

應用

葡萄糖四糖(Glc4)用作分析尿糖四糖(庞贝氏症和其他糖原贮积病的生物标志物)的参考。

包裝

无底玻璃瓶。内含物在插入的融合锥体内。

其他說明

为了全面了解我们针对客户研究提供的各种单糖产品,建议您访问我们的碳水化合物分类页面。

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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Yoav H Messinger et al.
Genetics in medicine : official journal of the American College of Medical Genetics, 14(1), 135-142 (2012-01-13)
Infantile Pompe disease resulting from a deficiency of lysosomal acid α-glucosidase (GAA) requires enzyme replacement therapy (ERT) with recombinant human GAA (rhGAA). Cross-reactive immunologic material negative (CRIM-negative) Pompe patients develop high-titer antibody to the rhGAA and do poorly. We describe
Victoria Manwaring et al.
Journal of inherited metabolic disease, 35(2), 311-316 (2011-06-21)
A high performance liquid chromatography method, adapted from an established urinary sugars method, has been developed for the analysis of a tetraglucose oligomer (Glc(4)) in urine. Pompe disease results from defects in the activity of lysosomal acid α-glucosidase (GAA) with
Zoheb B Kazi et al.
Genetics in medicine : official journal of the American College of Medical Genetics, 21(4), 887-895 (2018-09-15)
To investigate immune tolerance induction with transient low-dose methotrexate (TLD-MTX) initiated with recombinant human acid α-glucosidase (rhGAA), in treatment-naïve cross-reactive immunologic material (CRIM)-positive infantile-onset Pompe disease (IOPD) patients. Newly diagnosed IOPD patients received subcutaneous or oral 0.4 mg/kg TLD-MTX for 3
Johannes Brettschneider et al.
Journal of neuroimmunology, 217(1-2), 95-101 (2009-11-03)
The serum level of IgM antibodies against Glc(alpha1,4)Glc(alpha) (GAGA4) is higher in relapsing remitting multiple sclerosis (RRMS) compared to other neurological disease (OND) patients and healthy controls (HC). Detecting the level of anti-GAGA4 antibody by enzyme immunoassay and total IgM
Mikael Schwarz et al.
Journal of the neurological sciences, 244(1-2), 59-68 (2006-02-17)
There is an unmet need to develop specific biomarkers for multiple sclerosis (MS) to aid in the diagnosis, improve the management of patients and the monitoring of the effectiveness of treatment. We have screened serum from patients with relapsing-remitting MS

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