所有图片(1)
About This Item
经验公式（希尔记法）:
C16H29NO3
CAS号:
分子量:
283.41
Beilstein:
9281984
MDL號碼:
分類程式碼代碼:
12352211
PubChem物質ID:
NACRES:
NA.28
推荐产品
产品名称
N-十二烷酰-L-高丝氨酸内酯, ≥96% (HPLC)
品質等級
化驗
≥96% (HPLC)
形狀
powder or crystals
光學活性
[α]/D -25±5°, c = 0.2 in methanol
技術
mass spectrometry (MS): suitable
顏色
white to off-white
適合性
conforms to structure for Proton NMR spectrum
儲存溫度
−20°C
SMILES 字串
O=C1OCC[C@@H]1NC(CCCCCCCCCCC)=O
InChI
1S/C16H29NO3/c1-2-3-4-5-6-7-8-9-10-11-15(18)17-14-12-13-20-16(14)19/h14H,2-13H2,1H3,(H,17,18)/t14-/m0/s1
InChI 密鑰
WILLZMOKUUPJSL-AWEZNQCLSA-N
相关类别
生化／生理作用
N -十二酰基- L -高丝氨酸内酯是 N -酰基-高丝氨酸内酯家族的成员。 N -酰基高丝氨酸内酯（AHL）调控革兰阴性菌如 埃希杆菌 和 沙门菌 的基因表达，参与群体感应、细菌间的细胞间通讯；关于综述，请参见 。细菌细胞间通讯已成为开发新型抗毒力药物的靶点 ，也是预防生物膜形成的研究热点 。
群体感应信号产生
危險聲明
危險分類
Aquatic Chronic 4
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
其他客户在看
Cytotoxicity of N-dodecanoyl-Lhomoserine lactone and 5-N-dodecyl resorcinol to human granulocytes and monocytes: a comparative study.
Sviridova, T. et al.
Central European Journal of Immunology, 38, 310-316 (2013)
G Brelles-Mariño et al.
Journal of biotechnology, 91(2-3), 197-209 (2001-09-22)
Quorum sensing (also called autoinduction) is a term that describes an environmental sensing system that allows bacteria to monitor their own population density. Autoinduction relies upon the interaction of a small diffusible signal molecule (the autoinducer) with a transcriptional activator
Sun-Yang Park et al.
Applied and environmental microbiology, 71(5), 2632-2641 (2005-05-05)
N-acylhomoserine lactones (AHLs) play an important role in regulating virulence factors in pathogenic bacteria. Recently, the enzymatic inactivation of AHLs, which can be used as antibacterial targets, has been identified in several soil bacteria. In this study, strain M664, identified
Nishaben M Patel et al.
PloS one, 11(10), e0163469-e0163469 (2016-10-06)
N-acyl L-homoserine lactones (AHLs) constitute a predominant class of quorum-sensing signaling molecules used by Gram-negative bacteria. Here, we report a sensitive and non-targeted HPLC-MS/MS method based on parallel reaction monitoring (PRM) to identify and quantitate known, unanticipated, and novel AHLs
Role of RpoS in stress resistance, quorum sensing and spoilage potential of Pseudomonas fluorescens.
Xiaoxiang Liu et al.
International journal of food microbiology, 270, 31-38 (2018-02-23)
Microorganism activities are considered the main cause of most food spoilage, leading to great economic losses. Pseudomonas fluorescens is a Gram-negative bacterium that is widely found in food and has high spoilage activity. RpoS is considered an important global regulator
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