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53747

Sigma-Aldrich

透明质酸 钠盐 来源于马链球菌

bacterial glycosaminoglycan polysaccharide

别名:

聚（β-葡萄糖醛酸-[1→3]-β-N-乙酰葡糖胺-[1→4]），交替

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About This Item

CAS号:
9067-32-7
分類程式碼代碼:
51202002
PubChem物質ID:
24878223
NACRES:
NA.25

生物源

(Streptococcus equi)

品質等級

200

形狀

powder or crystals

分子量

~1.5-1.8 x 10E6 Da

雜質

≤1% protein

顏色

white

溶解度

H2O: 5 mg/mL, clear, colorless

儲存溫度

−20°C

SMILES 字串

[Na+].CC(=O)N[C@@H]1C[C@H](O)[C@@H](CO)O[C@H]1O[C@H]2[C@H](O)[C@@H](O)[C@H](O)O[C@@H]2C([O-])=O

InChI

1S/C28H44N2O23.Na/c1-5(33)29-9-18(11(35)7(3-31)47-25(9)46)49-28-17(41)15(39)20(22(53-28)24(44)45)51-26-10(30-6(2)34)19(12(36)8(4-32)48-26)50-27-16(40)13(37)14(38)21(52-27)23(42)43;/h7-22,25-28,31-32,35-41,46H,3-4H2,1-2H3,(H,29,33)(H,30,34)(H,42,43)(H,44,45);/q;+1/t7-,8-,9-,10-,11-,12-,13+,14+,15-,16-,17-,18-,19-,20+,21+,22+,25-,26+,27-,28-;/m1./s1

InChI 密鑰

YWIVKILSMZOHHF-QJZPQSOGSA-N

相关类别

一般說明

透明质酸（HA）是中枢神经系统细胞外基质的重要组分，是在所有脊椎动物结缔组织中都能发现的多功能大分子。这种超分子糖胺聚糖是一种聚阴离子天然聚合物，以线性多糖的形式存在。它由葡萄糖醛酸和N-乙酰氨基葡萄糖通过β-1,4键重复组成。透明质酸在眼睛、关节和心脏瓣膜中大量存在。

應用

马链球菌透明质酸钠盐已用于：
  • 与甲基丙烯酸酐合成交联甲基丙烯酸 HA 水凝胶（Coll-MeHA）
  • 在磷酸盐缓冲盐水（PBS）中取代 PBS 浴槽来改变润滑剂成分
  • 制备润滑剂，以研究对人体骨关节炎（OA）软骨边界润滑的影响

生化／生理作用

透明质酸（HA）是滑膜液和关节软骨的重要组分，起边界润滑剂的作用。它具有多种物理化学性质，包括生物可降解性、生物相容性、无毒性和非免疫原性。透明质酸被认为是生物医学用途的重要工具，如药物输送、组织工程、整形外科、眼科手术和骨关节炎手术。它参与身体缓冲和润滑。这种强大的抗氧化剂可以将水与组织结合。

其他說明

为了全面了解我们针对客户研究提供的各种多糖产品，建议您访问我们的碳水化合物分类页面。

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 2

閃點（°F）

Not applicable

閃點（°C）

Not applicable

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Extracellular matrix (ECM) is widely used as an inductive biological scaffold to repair soft tissue after injury by promoting functional site-appropriate remodeling of the implanted material. However, there is a lack of non-invasive analysis methods to monitor the remodeling characteristics
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Glycosaminoglycan Sulfation and Signaling

Glycosaminoglycans are large linear polysaccharides constructed of repeating disaccharide units.

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