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Merck
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Key Documents

52471

Sigma-Aldrich

异硫氰酸荧光素-葡聚糖

average mol wt 2,000,000

别名:

FITC– 葡聚糖 2000, FITC-右旋糖酐

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About This Item

CAS号:
60842-46-8
MDL號碼:
MFCD00131092
分類程式碼代碼:
12352201
NACRES:
NA.32

生物源

synthetic

共軛

FITC conjugate

形狀

powder or crystals

分子量

average mol wt 2,000,000

標籤範圍

0.001-0.020 mol FITC per mol glucose (substitution)

螢光

λex 493 nm; λem 520 nm in 0.1 M Tris pH 8.0

應用

cell analysis

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應用

异硫氰酸荧光素-葡聚糖（FITC-Dextran 2000）被用作荧光探针来研究结构的渗透性，例如参与听觉和血管渗透性过程的细胞间连接以及血脑屏障（BBB）的完整性等。
用异硫氰酸荧光素标记的葡聚糖可用于动物的灌注研究。

象形圖

Exclamation mark
GHS07

訊號詞

Warning

危險聲明

H315,H319,H335

危險分類

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

標靶器官

Respiratory system

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

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Elodie Debefve et al.
Lasers in surgery and medicine, 43(7), 696-704 (2011-11-08)
Photodynamic therapy (PDT) affects vascular barrier function and thus increases vessel permeability. This phenomenon may be exploited to facilitate targeted drug delivery and may lead to a new clinical application of photodynamic therapy. Here, we investigate the role of leukocyte
Albert Y Jin et al.
BMC neuroscience, 11, 12-12 (2010-02-04)
The link between early blood- brain barrier (BBB) breakdown and endothelial cell activation in acute stroke remain poorly defined. We hypothesized that P-selectin, a mediator of the early phase of leukocyte recruitment in acute ischemia is also a major contributor
Mercy Afadzi et al.
IEEE transactions on ultrasonics, ferroelectrics, and frequency control, 60(1), 21-33 (2013-01-05)
The mechanism involved in the ultrasoundenhanced intracellular delivery of fluorescein-isothiocyanate (FITC)-dextran (molecular weight 4 to 2000 kDa) and liposomes containing doxorubicin (Dox) was studied using HeLa cells and an ultrasound transducer at 300 kHz, varying the acoustic power. The cellular
Guiliang Zheng et al.
BMC neuroscience, 13, 71-71 (2012-06-21)
Exposure to intense noise causes the excessive movement of the organ of Corti, stretching the organ and compromising sensory cell functions. We recently revealed changes in the transcriptional expression of multiple adhesion-related genes during the acute phases of cochlear damage
Sangmi Ock et al.
Biochemical and biophysical research communications, 516(2), 350-356 (2019-06-19)
Receptor activator of NF-κB ligand (RANKL) is a member of the TNF superfamily. RANKL increases endothelial permeability and induces angiogenesis, suggesting its critical roles in the vasculature. Despite the evidence implicating RANKL in vascular pathology, its role in ischemic retinopathy
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FITC-labelled polysaccharides

Additional information about FITC-labelled polysaccarides including FITC-Dextran, FITC-DEAE-dextran (FDD), FITC-carboxymethyl-dextran (FCM-Dextran). This page discusses the impact of weight-average molecular weight on the respective molecule dimensions and other physical properties

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