44977
DISBAC2(3), Voltage Sensitive Probe
≥98% (HPLC)
别名:
5-[3-(1,3-Diethylhexahydro-4,6-dioxo-2-thioxo-5-pyrimidinyl)-2-propen-1-ylidene]-1,3-diethyldihydro-2-thioxo-4,6(1H,5H)-pyrimidinedione, Bis(1,3-diethylthiobarbituric acid)trimethine oxonol
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所有图片(1)
About This Item
经验公式（希尔记法）:
C19H24N4O4S2
CAS号:
分子量:
436.55
Beilstein:
1232950
EC號碼:
MDL號碼:
分類程式碼代碼:
12352108
PubChem物質ID:
NACRES:
NA.32
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品質等級
化驗
≥98% (HPLC)
螢光
λex 535 nm; λem 560 nm in DMSO
適合性
complies for Infrared spectrum
儲存溫度
−20°C
SMILES 字串
CCN1C(=O)C(\C=C\C=C2\C(=O)N(CC)C(=S)N(CC)C2=O)C(=O)N(CC)C1=S
InChI
1S/C19H24N4O4S2/c1-5-20-14(24)12(15(25)21(6-2)18(20)28)10-9-11-13-16(26)22(7-3)19(29)23(8-4)17(13)27/h9-12H,5-8H2,1-4H3/b10-9+
InChI 密鑰
VJYNRXFXHKIGLT-MDZDMXLPSA-N
應用
DISBAC2(3), Voltage Sensitive Probe is used for single-cell fluorescence imaging of transmembrane conductance and potential change.
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
S Amoroso et al.
Biochimica et biophysica acta, 1239(1), 67-73 (1995-10-04)
In this study the effect of the A1 agonist 2-chloro-N6-cyclopentyladenosine (CCPA) on bis(1,3-diethylthiobarbituric acid)trimethine oxonol (bisoxonol)-monitored membrane potential in cerebrocortical nerve endings was evaluated. CCPA (30, 100 and 300 microM) caused a dose-dependent decrease of high K(+)- and veratridine-induced membrane
S Bouhdid et al.
Journal of applied microbiology, 109(4), 1139-1149 (2010-05-12)
To study cellular damage induced by Cinnamomum verum essential oil in Pseudomonas aeruginosa ATCC 27853 and Staphylococcus aureus ATCC 29213. The effect of cinnamon bark essential oil on these two strains was evaluated by plate counts, potassium leakage, flow cytometry
N Minami et al.
Journal of neural transmission. General section, 97(1), 65-72 (1994-01-01)
Effects of cyclic AMP on membrane potentials were examined by measuring the changes of bis-oxonol fluorescence in bovine adrenal medullary chromaffin cells. 8-Bromo cyclic AMP (8Br-cAMP) or forskolin caused a gradual and long lasting increase of the fluorescence intensity. The
Flow cytometric analysis of altered mononuclear cell transmembrane potential induced by cyclosporin.
M K Tanner et al.
Cytometry, 14(1), 59-69 (1993-01-01)
Immunosuppression by the fungal metabolite cyclosporin A (CsA) is characterized by functional inhibition, rather than destruction of cells. Because activation of immune cells involves intracellular signalling events associated with modulations of cell transmembrane potential (TMP), we tested the ability of
Mikiyo Yamaguchi et al.
Anesthesia and analgesia, 100(2), 419-426 (2005-01-28)
The membrane potential of endothelial cells is an important determinant of endothelial functions, including regulation of vascular tone. We investigated whether adenosine triphosphate-sensitive potassium (K(ATP)) channels were involved in the response of membrane potential to hyperosmolality in cultured human aorta
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