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生物源
rabbit
品質等級
100
500
共軛
unconjugated
抗體表格
Ig fraction of antiserum
抗體產品種類
primary antibodies
無性繁殖
polyclonal
描述
For In Vitro Diagnostic Use in Select Regions (See Chart)
形狀
buffered aqueous solution
物種活性
human
包裝
vial of 0.1 mL concentrate (413A-14)
vial of 0.5 mL concentrate (413A-15)
bottle of 1.0 mL predilute (413A-17)
vial of 1.0 mL concentrate (413A-16)
bottle of 7.0 mL predilute (413A-18)
製造商／商標名
Cell Marque™
技術
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:25-1:100
控制
embryonal carcinoma, yolk sac tumor
運輸包裝
wet ice
儲存溫度
2-8°C
視覺化
membranous
基因資訊
human ... SLC2A3(6515)
一般說明
Glucose transporter membrane 3 (GLUT3) is known as a solute carrier family 2 (facilitated glucose transporter) member 3 and represents a membrane bound glucose transporter. In one study scientists, using immunoprecipitation and western blot technologies, detected GLUT3 expression in spermatozoa of testis and brain but not in other types of tissue. In-house research via immunohistochemistry confirmed GLUT3 expression in testis/spermatozoa, but no GLUT3 was detected in brain. In a study conducted by Howitt BE et. al. anti-GLUT3 demonstrated membranous staining of seminoma cells in 44 cases (65%) of total 67 specimens. In addition, anti-GLUT3 labeled embryonal carcinoma (20/20) and yolk sac tumor (8/8) with 100% sensitivity.GLUT3 is not expressed in non-germ cell tumors such as leydig cell tumor and adenomatoid tumor.Spermatocytic seminoma, choriocarcinoma, and immature teratoma are also negative for GLUT3. Therefore, anti-GLUT3 is a very useful IHC marker to include in a panel for identification of germ cell tumors.
品質
 IVD |  IVD |  IVD |  RUO |
聯結
GLUT3 Positive Control Slides, Product No. 413S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).
外觀
Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide
準備報告
Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.
其他說明
For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com
法律資訊
Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany
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Brooke E Howitt et al.
Applied immunohistochemistry & molecular morphology : AIMM, 21(5), 401-407 (2013-01-25)
Testicular germ cell tumors (TGCT) are the most common type of testicular tumor and encompass different histologic types that greatly influence treatment and prognosis. Immunohistochemical studies may be required for accurate classification, particularly when these tumors present at extragonadal sites
R S Haber et al.
Endocrinology, 132(6), 2538-2543 (1993-06-01)
The tissue distribution of the GLUT3 glucose transporter protein was examined in human tissues using a rabbit antiserum directed against the C-terminal peptide sequence of human GLUT3. This anti-serum was shown to recognize the human GLUT3 protein in Chinese hamster
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