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Merck

39286

Sigma-Aldrich

羟基司替丁双(甲磺酸酯)

suitable for fluorescence, ≥96.0% (HPLC)

别名:

2-羟基二苯乙烯-4,4′-二羧氨基脒双(甲磺酸), 氟金, 2-羟基二苯乙烯-4,4′-二羧氨基脒双, 氟金

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About This Item

经验公式(希尔记法):
C18H24N4O7S2
分子量:
472.54
MDL號碼:
分類程式碼代碼:
41116100
PubChem物質ID:
NACRES:
NA.32

化驗

≥96.0% (HPLC)

形狀

powder

螢光

λex 318 nm; λem 560 nm in TBE Buffer

適合性

suitable for fluorescence

儲存溫度

2-8°C

SMILES 字串

CS(O)(=O)=O.CS(O)(=O)=O.NC(=N)c1ccc(cc1)\C=C\c2ccc(cc2O)C(N)=N

InChI

1S/C16H16N4O.2CH4O3S/c17-15(18)12-5-2-10(3-6-12)1-4-11-7-8-13(16(19)20)9-14(11)21;2*1-5(2,3)4/h1-9,21H,(H3,17,18)(H3,19,20);2*1H3,(H,2,3,4)/b4-1+;;

InChI 密鑰

YGNSQKCULHSJDC-HFPMQDOPSA-N

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一般說明

羟基苯胺双(甲磺酸),又称荧光金,是一种逆行荧光示踪剂。在化学上,羟基苯胺是一种弱碱,可以其不带电的形式穿过细胞膜。

羟基苯胺双(甲磺酸)的部分性质包括:

  • 强烈的荧光反应。
  • 广泛树突填充。
  • 较高的抗褪色性。
  • 未受损纤维无法吸收。
  • 标记细胞不扩散。
  • 与其他神经组织化学技术高度兼容。

應用

羟基苯胺双(甲磺酸)或荧光金(FG)可用于标记神经元,并研究听力损失的早期影响。它可用于通过标记细胞来研究CNS内广泛轴突投射的形态学特征。
羟芪巴脒(甲磺酸)是一种荧光逆行示踪剂(轴突转运),在显微解剖学研究中用于神经定位。

象形圖

Exclamation mark

訊號詞

Warning

危險聲明

危險分類

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

標靶器官

Respiratory system

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves


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L C Schmued et al.
Brain research, 377(1), 147-154 (1986-07-02)
A new fluorescent dye, Fluoro-Gold, has been demonstrated to undergo retrograde axonal transport. Its properties include intense fluorescence, extensive filling of dendrites, high resistance to fading, no uptake by intact undamaged fibers of passage, no diffusion from labeled cells, consistent
Miyako Hatano et al.
Hearing research, 287(1-2), 57-66 (2012-06-26)
The purpose of this study was to investigate the effects of early hearing loss on the anatomy of the central auditory system, specifically, the ascending projections to the inferior colliculus (IC). We compared normal animals with animals deafened during early
N Kuwabara
Biotechnic & histochemistry : official publication of the Biological Stain Commission, 87(6), 413-422 (2012-06-21)
A method is described for studying the morphological features of extensive axonal projections within the central nervous system of the gerbil, Meriones anguiculatus. Potentially long descending axonal projections between the auditory thalamus and lower brainstem were used as a model.
Tímea Bácskai et al.
Brain structure & function, 219(1), 303-321 (2013-01-05)
We have mapped the motor neurons (MNs) supplying the major hindlimb muscles of transgenic (C57/BL6J-ChAT-EGFP) and wild-type (C57/BL6J) mice. The fluorescent retrograde tracer Fluoro-Gold was injected into 19 hindlimb muscles. Consecutive transverse spinal cord sections were harvested, the MNs counted

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