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Merck

21955

Sigma-Aldrich

5(6)-羧基四甲基罗丹明N-琥珀酰亚胺酯

BioReagent, suitable for fluorescence, ≥70% (coupling to amines)

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About This Item

经验公式(希尔记法):
C29H25N3O7
分子量:
527.52
Beilstein:
8739319
MDL號碼:
分類程式碼代碼:
12352116
PubChem物質ID:
NACRES:
NA.32

產品線

BioReagent

化驗

≥70% (coupling to amines)

形狀

powder

溶解度

DMF: soluble
acetonitrile: soluble
methanol: soluble

螢光

λex 543 nm; λem 576 nm in methanol
λex 554 nm; λem 584 nm in 0.1 M phosphate pH 8.0

適合性

suitable for fluorescence

儲存溫度

−20°C

SMILES 字串

CN(C)c1ccc2c(Oc3cc(ccc3C24OC(=O)c5cc(ccc45)C(=O)ON6C(=O)CCC6=O)N(C)C)c1

InChI

1S/C29H25N3O7/c1-30(2)17-6-9-21-23(14-17)37-24-15-18(31(3)4)7-10-22(24)29(21)20-8-5-16(13-19(20)28(36)38-29)27(35)39-32-25(33)11-12-26(32)34/h5-10,13-15H,11-12H2,1-4H3

InChI 密鑰

CXYYHBMOVJJZTD-UHFFFAOYSA-N

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應用

5(6)-羧四甲基罗丹明 N-琥珀酰亚胺酯(TMR-SE)可用作胺偶联剂,以形成5(6)-羧四甲基罗丹明(TMR)衍生的化合物,例如蛋白质和药物。

包裝

无底玻璃瓶。内含物在插入的融合锥体内。

其他說明

罗丹明衍生标签,可用于胺修饰和蛋白质缀合

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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L D Mayfield et al.
Bioorganic & medicinal chemistry letters, 9(10), 1419-1422 (1999-06-09)
Resins for solid-phase synthesis can affect coupling efficiencies by interacting with reactants. We have observed that polyethylene glycol-polystyrene (PEG-PS) solid support absorbs added activated fluorophores, preventing efficient labeling of peptide nucleic acids (PNAs). We now report that addition of an
Divyamani Srinivasan et al.
PloS one, 6(3), e17732-e17732 (2011-03-23)
Cell-penetrating peptides (CPPs) can transport macromolecular cargos into live cells. However, the cellular delivery efficiency of these reagents is often suboptimal because CPP-cargo conjugates typically remain trapped inside endosomes. Interestingly, irradiation of fluorescently labeled CPPs with light increases the release
E. Koller
Appl. Fluoresc. Technol., 3, 20-20 (1991)
P Kask et al.
Biophysical journal, 78(4), 1703-1713 (2000-03-29)
A method of sample analysis is presented which is based on fitting a joint distribution of photon count numbers. In experiments, fluorescence from a microscopic volume containing a fluctuating number of molecules is monitored by two detectors, using a confocal
Yoshiaki Yano et al.
Biochemistry, 41(9), 3073-3080 (2002-02-28)
Investigation of interactions between hydrophobic model peptides and lipid bilayers is perhaps the only way to elucidate the principles of the folding and stability of membrane proteins (White, S. H., and Wimley, W. C. (1998) Biochim. Biophys. Acta 1367, 339-352).

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