跳转至内容
Merck
所有图片(1)

主要文件

171R-1

Sigma-Aldrich

CD71 (EP232) Rabbit Monoclonal Primary Antibody

别名:

TFR1, TRF, TRFR, Transferrin Receptor 1, p90, transferrin receptor (p90, CD71)

登录查看公司和协议定价


About This Item

分類程式碼代碼:
12352203
NACRES:
NA.41

生物源

rabbit

品質等級

100
500

共軛

unconjugated

抗體表格

culture supernatant

抗體產品種類

primary antibodies

無性繁殖

EP232, monoclonal

描述

For In Vitro Diagnostic Use in Select Regions (See Chart)

形狀

buffered aqueous solution

物種活性

human

包裝

vial of 0.1 mL concentrate (171R-14)
vial of 0.1 mL concentrate Research Use Only (171R-14-RUO)
vial of 0.5 mL concentrate (171R-15)
vial of 1.0 mL concentrate (171R-16)
vial of 1.0 mL concentrate Research Use Only (171R-16-RUO)
vial of 1.0 mL pre-dilute Research Use Only (171R-17-RUO)
vial of 1.0 mL predilute ready-to-use (171R-17)
vial of 7.0 mL pre-dilute ready-to-use Research Use Only (171R-18-RUO)
vial of 7.0 mL predilute ready-to-use (171R-18)

製造商/商標名

Cell Marque®

技術

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:200 (concentrated)

同型

IgG

控制

bone marrow

運輸包裝

wet ice

儲存溫度

2-8°C

視覺化

cytoplasmic, membranous

一般說明

Transferrin receptor 1 (CD71) is expressed on placental syncytiotrophoblasts, myocytes, basal keratinocytes, hepatocytes, endocrine pancreas, spermatocytes, and erythroid precursors. The level of transferrin receptor expression is highest in early erythroid precursors through the intermediate normoblast phase, after which expression decreases through the reticulocyte phase. The maturation of erythrocytes results in loss of transferrin receptor expression. AntiCD71 is useful in identifying erythroid precursors. The high level of transferrin receptor within erythroid precursors makes anti-CD71 an excellent marker for evaluation of erythroid precursors within bone marrow biopsy specimens and shows the following features: 1) distinct membranous and cytoplasmic staining pattern, which is easily recognized in bone marrow biopsy; 2) restriction to erythroid lineage within bone marrow biopsy specimens; 3) CD71 expression decreases with the maturation of erythrocytes, with the highest level seen in early forms and the lowest level in late normoblast stage, and most importantly; 4) mature erythrocytes do not express CD71.

品質

United States - IVD
Canada - IVD
European Union - IVD
Japan - RUO

聯結

CD71 Positive Control Slides, Product No. 171S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

外觀

Predilute: diluted in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide
Concentrate: diluted in Phosphate Buffered Saline, pH 7.2, with 1% BSA and <0.1% Sodium Azide

準備報告

Download the IFU specific to your product lot and format
Note: This requires a keycode which can be found on your packaging or product label.

Download the latest released IFU
Note: This IFU may not apply to your specific product lot.

其他說明

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

法律資訊

Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany

未找到合适的产品?  

试试我们的产品选型工具.

儲存類別代碼

12 - Non Combustible Liquids

水污染物質分類(WGK)

WGK 2

閃點(°F)

Not applicable

閃點(°C)

Not applicable


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

没有发现合适的版本?

如果您需要特殊版本,可通过批号或批次号查找具体证书。

已有该产品?

在文件库中查找您最近购买产品的文档。

访问文档库

Changes in cell surface antigen expression during hemopoietic differentiation.
Sieff C, Bicknell D, Caine G, et al.
Blood, 60(3), 703-713 (1982)
Expression of transferrin receptor on murine hematopoietic progenitors.
Lesley J, Hyman R, Schulte R, et al.
Cellular Immunology, 83(1), 14-25 (1984)
Cell surface antigen expression in human erythroid progenitors: erythroid and megakaryocytic markers.
Nakahata T and Okumura N
Leukemia & Lymphoma, 13(5-6), 401-409 (1994)
T Nakahata et al.
Leukemia & lymphoma, 13(5-6), 401-409 (1994-05-01)
This review summarizes the changes in cell surface antigen expression during proliferation and differentiation of human erythroid progenitors. The content is based on our experimental data obtained from complement-mediated cytotoxicity assays against hematopoietic progenitors and a combined technique of sequential
P Ponka et al.
The international journal of biochemistry & cell biology, 31(10), 1111-1137 (1999-12-03)
The transferrin receptor is a membrane glycoprotein whose only clearly defined function is to mediate cellular uptake of iron from a plasma glycoprotein, transferrin. Iron uptake from transferrin involves the binding of transferrin to the transferrin receptor, internalization of transferrin

我们的科学家团队拥有各种研究领域经验,包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系技术服务部门