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密度
1.01 g/mL at 20 °C
儲存溫度
2-8°C
SMILES 字串
Cl[Co]Cl
InChI
1S/2ClH.Co/h2*1H;/q;;+2/p-2
InChI 密鑰
GVPFVAHMJGGAJG-UHFFFAOYSA-L
應用
0.1M 氯化钴溶液已被用于模拟前列腺癌细胞的低氧暴露和 HIF-1（缺氧诱导因子 1）的表达。其已用于诱导人肠上皮细胞缺氧。
生化／生理作用
氯化钴通过上调缺氧诱导因子-1α 诱导细胞缺氧 (HIF-1α)、促红细胞生成素和糖酵解酶。它也是大鼠神经元 PC12 细胞线粒体 DNA 损伤的原因。其也负责诱导细胞凋亡。
0.1M 氯化钴溶液是添加剂筛选试剂盒的添加剂筛选液。添加剂筛选试剂盒设计用于快速方便地评价添加剂及其影响样品结晶的能力。添加剂试剂盒为精制结晶条件提供了工具。
0.1M 氯化钴溶液是添加剂筛选试剂盒的添加剂筛选液。添加剂筛选试剂盒设计用于快速方便地评价添加剂及其影响样品结晶的能力。添加剂试剂盒为精制结晶条件提供了工具。
訊號詞
Danger
危險聲明
危險分類
Aquatic Chronic 2 - Carc. 1B - Repr. 1B
儲存類別代碼
6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
其他客户在看
CoCl(2) induces apoptosis via the 18 kDa translocator protein in U118MG human glioblastoma cells.
Zeno S, et al.
Biochemistry, 48, 4652-4652 (2009)
Exposure to hypoxia following irradiation increases radioresistance in prostate cancer cells.
Hennessey D, et al.
Urologic Oncology, 31, 1106-1106 (2013)
Downregulation of duodenal SLC transporters and activation of proinflammatory signaling constitute the early response to high altitude in humans.
Wojtal KA, et al.
American Journal of Physiology: Gastrointestinal and Liver Physiology, 307, G673-G673 (2014)
Mengxin Lu et al.
Cell death & disease, 9(10), 1046-1046 (2018-10-14)
Cold-inducible RNA binding protein (CIRBP) has been reported to be associated with distinct tumorigenesis. In this study, we investigated the role of CIRBP in human bladder cancer (BCa), indicating that CIRBP is overexpressed in BCa tissues and cell lines to
Mitochondrial DNA damage and a hypoxic response are induced by CoCl(2) in rat neuronal PC12 cells.
Wang G, et al.
Nucleic Acids Research, 28, 2135-2135 (2000)
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