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Merck

04476

Sigma-Aldrich

大麦芽碱

≥97.0% (HPLC)

别名:

2-(4-羟基苯基)-N,N-二甲基乙胺, 4-(2-二甲基氨基乙基)苯酚, N,N-二甲基酪胺, 羟基-N,N-二甲基苯乙胺, 仙影拳碱, 大麦碱, 大麦胺, 大麦芽碱

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About This Item

经验公式(希尔记法):
C10H15NO
CAS号:
分子量:
165.23
Beilstein:
2207615
EC號碼:
MDL號碼:
分類程式碼代碼:
41116107
PubChem物質ID:
NACRES:
NA.25

品質等級

化驗

≥97.0% (HPLC)

形狀

powder or crystals

應用

metabolomics
vitamins, nutraceuticals, and natural products

SMILES 字串

CN(C)CCc1ccc(O)cc1

InChI

1S/C10H15NO/c1-11(2)8-7-9-3-5-10(12)6-4-9/h3-6,12H,7-8H2,1-2H3

InChI 密鑰

KUBCEEMXQZUPDQ-UHFFFAOYSA-N

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應用

大麦芽碱适合用于研究芦苇金丝雀草生物碱对体外消化率的影响。它也适合作为标准品用于通过HPLC/二极管阵列检测分析对未发芽和发芽的大麦中内源大麦芽碱进行鉴定。大麦芽碱可作为分析参考材料,并用于研究苯乙胺型生物碱的活性。

生化/生理作用

大麦芽碱是一种生物碱,发现于植物,如麦芽和海藻的根中。它是酪氨酸代谢的一种代谢产物,可由酪胺通过先后两次的N-甲基化反应而进行生物合成,它可通过单胺氧化酶而被代谢。大麦芽碱是一种拟交感神经药,因偶尔能够在赛跑后的尿液样品中发现而引发对其药理作用的关注。大麦芽碱可通过抑制环磷腺苷酸(cAMP)的产生而对黑色素生成进行抑制。cAMP可参与到黑色素生成相关蛋白的表达。大麦芽碱可被用于抑制色素沉着。它从种子萌芽的第一天起就存在于大麦的根中,但其并不存在于种子中。

包裝

无底玻璃瓶。内含物在插入的融合锥体内。

象形圖

Exclamation mark

訊號詞

Warning

危險聲明

危險分類

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

標靶器官

Respiratory system

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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分析证书(COA)

Lot/Batch Number

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T Wainwright et al.
IARC scientific publications, (41)(41), 71-80 (1982-01-01)
NDMA is formed in malt because NOx reacts with certain amines in germinated barley when it is kilned. Hordenine is the major precursor of NDMA, although gramine and sarcosine can possibly contribute minor amounts. The hordenine is formed in the
D L Liu et al.
Journal of chemical ecology, 19(10), 2231-2244 (1993-10-01)
The release of alkaloids by barley was quantified by HPLC. Hordenine was released from the roots of barley in a hydroponic system for up to 60 days. The amount reached a maximum, 2μg/plant/day, at 36 days, then declined. Effects on
M M Mangino et al.
IARC scientific publications, (57)(57), 337-346 (1984-01-01)
The two tertiary amine alkaloids, hordenine and gramine, which are biosynthesized in malt during germination, were subjected to nitrosation under conditions typical for the study of tertiary amine nitrosation. At 65 degrees C in dilute aqueous acid (pH 4.4 or
M F Goelz et al.
Toxicology, 18(2), 125-131 (1980-01-01)
Meadow voles (Microtus pennsylvanicus) were used to evaluate the relative toxicity of the alkaloids, gramine and hordenine, which are present in reed canarygrass (Phalaris arundinacea) and to assess their effects on the quality of this grass as a forage. One
M Frank et al.
Equine veterinary journal, 22(6), 437-441 (1990-11-01)
Hordenine is an alkaloid occurring naturally in grains, sprouting barley, and certain grasses. It is occasionally found in post race urine samples, and therefore we investigated its pharmacological actions in the horse. Hordenine (2.0 mg/kg bodyweight [bwt]) was administered by

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