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Merck

01912

Sigma-Aldrich

N-乙酰-D-鞘氨醇

≥98.0% (TLC)

别名:

N-乙酰基-D-红鞘氨醇, C2 神经酰胺(d18:1/2:0), C2 神经酰胺, 乙酰神经酰胺, (2S,3R,4E)-2-(乙酰基氨基)-4-十八烯-1,3-二醇

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About This Item

经验公式(希尔记法):
C20H39NO3
分子量:
341.53
MDL號碼:
分類程式碼代碼:
12352211
PubChem物質ID:
NACRES:
NA.85

品質等級

化驗

≥98.0% (TLC)

脂質類型

sphingolipids

儲存溫度

−20°C

SMILES 字串

CCCCCCCCCCCCC\C=C\[C@H](O)[C@@H](CO)NC(C)=O

InChI

1S/C20H39NO3/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-20(24)19(17-22)21-18(2)23/h15-16,19-20,22,24H,3-14,17H2,1-2H3,(H,21,23)/b16-15+/t19-,20+/m1/s1

InChI 密鑰

BLTCBVOJNNKFKC-HEQKZDDYSA-N

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生化/生理作用

具有细胞可渗透性、生物活性的神经酰胺。它诱导细胞分化和凋亡,并可激活蛋白磷酸酶。

包裝

Bottomless glass bottle. Contents are inside inserted fused cone.

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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Ceramidases are key enzymes that decrease ceramide levels in cells. A reduction in ceramide concentration impairs ceramide signalling, and results in apoptosis resistance in cancer cells. This study investigates the potential for ceranib-2, a novel ceramidase inhibitor, to affect the
Wei Wang et al.
PloS one, 10(4), e0119005-e0119005 (2015-04-24)
Conjugated linoleic acid (CLA) reduces adiposity in human and mouse adipocytes. This outcome is achieved through a variety of biological responses including increased energy expenditure and fatty acid oxidation, increased inflammation, repression of fatty acid biosynthesis, attenuated glucose transport, and

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