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Merck

S2252

Sigma-Aldrich

亚硝酸钠

ReagentPlus®, ≥99.0%

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About This Item

线性分子式:
NaNO2
CAS号:
分子量:
69.00
EC號碼:
MDL號碼:
分類程式碼代碼:
12352302
PubChem物質ID:
NACRES:
NA.21
化驗:
≥99.0%
形狀:
powder or crystals

品質等級

產品線

ReagentPlus®

化驗

≥99.0%

形狀

powder or crystals

自燃溫度

914 °F

pH值

9 (20 °C, 100 g/L)

mp

271 °C (lit.)

SMILES 字串

[Na+].[O-]N=O

InChI

1S/HNO2.Na/c2-1-3;/h(H,2,3);/q;+1/p-1

InChI 密鑰

LPXPTNMVRIOKMN-UHFFFAOYSA-M

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一般說明

亚硝酸钠是一种具有还原性和氧化性的空气敏感和吸湿性固体。它是合成有机化学中常用的试剂和催化剂。它被酸(甚至弱酸)分解,形成棕色的氮氧化物混合物(NOx)。

應用

亚硝酸钠可作为试剂用于:      
  • 在将胺转化为重氮化合物的过程中,重氮化合物被用作许多染料的关键前体,如重氮染料。      
  • Nef 反应和 Abidi 转化。      
  • 在 TFA 和有氧条件下的 C-C 键裂解反应。      
  • 在 K2S2O8 环境下烯烃的氧化羰化反应。

在有机合成中也可用作硝化剂。
它用于直接碳氢硝化、同位硝化和过渡金属催化的交叉偶联硝化。在有氧、无溶剂条件下,NaNO2 也被用作醇催化氧化的助催化剂。

法律資訊

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany

訊號詞

Danger

危險分類

Acute Tox. 3 Oral - Aquatic Acute 1 - Eye Irrit. 2 - Ox. Sol. 3

儲存類別代碼

5.1B - Oxidizing hazardous materials

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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Arda Gülay et al.
mBio, 10(6) (2019-11-07)
Nitrification, the oxidative process converting ammonia to nitrite and nitrate, is driven by microbes and plays a central role in the global nitrogen cycle. Our earlier investigations based on 16S rRNA and amoA amplicon analysis, amoA quantitative PCR and metagenomics
Anne C Rios et al.
Cancer cell, 35(4), 618-632 (2019-04-02)
Breast tumors are inherently heterogeneous, but the evolving cellular organization through neoplastic progression is poorly understood. Here we report a rapid, large-scale single-cell resolution 3D imaging protocol based on a one-step clearing agent that allows visualization of normal tissue architecture
Lucas C Pinheiro et al.
Free radical biology & medicine, 53(4), 701-709 (2012-06-23)
The new pathway nitrate-nitrite-nitric oxide (NO) has emerged as a physiological alternative to the classical enzymatic pathway for NO formation from l-arginine. Nitrate is converted to nitrite by commensal bacteria in the oral cavity and the nitrite formed is then
Edward H Oldfield et al.
Journal of neurosurgery, 119(3), 634-641 (2013-05-28)
Intravenous sodium nitrite has been shown to prevent and reverse cerebral vasospasm in a primate model of subarachnoid hemorrhage (SAH). The present Phase IIA dose-escalation study of sodium nitrite was conducted to determine the compound's safety in humans with aneurysmal
Paul J Shami et al.
Journal of medicinal chemistry, 49(14), 4356-4366 (2006-07-11)
The literature provides evidence that metabolic nitric oxide (NO) release mediates the cytotoxic activities (against human leukemia and prostate cancer xenografts in mice) of JS-K, a compound of structure R(2)N-N(O)=NO-Ar for which R(2)N is 4-(ethoxycarbonyl)piperazin-1-yl and Ar is 2,4-dinitrophenyl. Here

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