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Merck

Y0001048

左羟丙哌嗪杂质C

European Pharmacopoeia (EP) Reference Standard

别名:

缩水甘油, 2,3-环氧-1-丙醇, Glycerolglycide, 环氧乙烷甲醇

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About This Item

经验公式(希尔记法):
C3H6O2
CAS号:
分子量:
74.08
Beilstein:
383562
MDL號碼:
分類程式碼代碼:
41116107
PubChem物質ID:
NACRES:
NA.24

等級

pharmaceutical primary standard

蒸汽密度

2.15 (vs air)

蒸汽壓力

0.9 mmHg ( 25 °C)

API 家族

levodropropizine

自燃溫度

780 °F

製造商/商標名

EDQM

折射率

n20/D 1.433 (lit.)

bp

61-62 °C/15 mmHg (lit.)

密度

1.117 g/mL at 25 °C (lit.)

應用

pharmaceutical (small molecule)

格式

neat

儲存溫度

−20°C

SMILES 字串

OCC1CO1

InChI

1S/C3H6O2/c4-1-3-2-5-3/h3-4H,1-2H2

InChI 密鑰

CTKINSOISVBQLD-UHFFFAOYSA-N

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一般說明

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

應用

Levodropropizine impurity C EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

包裝

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

其他說明

Sales restrictions may apply.

象形圖

Skull and crossbonesHealth hazard

訊號詞

Danger

危險分類

Acute Tox. 2 Inhalation - Acute Tox. 4 Dermal - Acute Tox. 4 Oral - Carc. 1B - Eye Irrit. 2 - Muta. 2 - Repr. 1B - Skin Irrit. 2 - STOT SE 3

標靶器官

Respiratory system

儲存類別代碼

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

水污染物質分類(WGK)

WGK 3

閃點(°F)

161.6 °F

閃點(°C)

72 °C


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分析证书(COA)

Lot/Batch Number

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Glycidol.
IARC monographs on the evaluation of carcinogenic risks to humans, 77, 469-486 (2000-12-02)
Hirotoshi Akane et al.
Journal of applied toxicology : JAT, 34(12), 1389-1399 (2014-01-08)
We previously found that exposure to glycidol at 1000 ppm in drinking water caused axonopathy in maternal rats and aberrations in late-stage hippocampal neurogenesis, targeting the process of neurite extension in offspring. To identify the profile of developmental neurotoxicity of
Kunio Wada et al.
Mutation research. Genetic toxicology and environmental mutagenesis, 769, 1-6 (2014-10-26)
The in vivo comet assay has been used for the evaluation of DNA damage and repair in various tissues of rodents. However, it can give false-positive results due to non-specific DNA damage associated with cell death. In this study, we
Hirotoshi Akane et al.
Toxicology and applied pharmacology, 279(2), 150-162 (2014-06-11)
We previously found that the 28-day oral toxicity study of glycidol at 200mg/kg/day in rats resulted in axonopathy in both the central and peripheral nervous systems and aberrations in the late-stage of hippocampal neurogenesis targeting the process of neurite extension.
Nadiya Bakhiya et al.
Molecular nutrition & food research, 55(4), 509-521 (2011-02-26)
Fatty acid esters of 3-chloropropane-1,2-diol (3-MCPD) and glycidol are a newly identified class of food process contaminants. They are widespread in refined vegetable oils and fats and have been detected in vegetable fat-containing products, including infant formulas. There are no

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