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Merck

SMB01333

Sigma-Aldrich

Acetyl-6-formylpterin

≥95% (HPLC)

别名:

2-Acetamido-4-oxopteridine-6-carboxaldehyde, 2-Acetamido-6-formylpteridin-4(3H)-one, 2-Acetylamino-4-hydroxy-6-formylpteridine, 2-Acetamido-6-formylpteridin-4-one, N-(6-formyl-4-hydroxy-2-pteridinyl)acetamide, N-(6-formyl-4-oxo-1H-pteridin-2-yl)acetamide

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About This Item

经验公式(希尔记法):
C9H7N5O3
CAS号:
分子量:
233.18
MDL號碼:
分類程式碼代碼:
12352205
NACRES:
NA.77

品質等級

化驗

≥95% (HPLC)

形狀

powder

儲存溫度

−20°C

SMILES 字串

CC(=O)NC1=NC2=NC=C(N=C2C(=O)N1)C=O

InChI

1S/C9H7N5O3/c1-4(16)11-9-13-7-6(8(17)14-9)12-5(3-15)2-10-7/h2-3H,1H3,(H2,10,11,13,14,16,17)

InChI 密鑰

DDBCPKAHJKOGKK-UHFFFAOYSA-N

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一般說明

Acetyl-6-formylpterin is a vitamin B9 (folate) metabolite and ligand to MHC class I-related protein 1 (MR1) antigens presented on mucosal-associated invariant T (MAIT) cells.
Acetyl-6-formylpterin, also known as 2-Acetamido-6-formylpteridin-4-one, is a pteridine derivative and a reductive amination product derived from folic acid. This unique compound undergoes a reductive amination reaction, generating formyl groups that can be subsequently acetylated or alkylated, resulting in the formation of stable compounds with diverse properties. Current research highlights the multifaceted nature of this compound, indicating its potential biological activities, including neuroprotective, antitumor, and anticancer properties.

Moreover, acetyl-6-formylpterin serves as a precursor in the synthesis of 2′-hydroxy-7,8-dihydrofolate, a metabolite associated with para-aminosalicylic acid (PAS) in M. tuberculosis. This compound′s versatility and involvement in various biological processes make it an intriguing molecule for metabolomics and biochemical research.

應用

Acetyl-6-formylpterin has been used:
  • to study the potential reversal of iver fibrosis
  • in metabolomics research

生化/生理作用

Acetyl-6-formylpterin is involved in the enzymatic conversion of GTP to BH4, playing a role in the regulation of neurotransmitter synthesis and other biological processes.

特點和優勢

  • Can be used in Metabolomics and Biochemical research
  • High-quality compound suitable for multiple research applications

其他說明

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儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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