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Merck

SMB00948

Sigma-Aldrich

trans-Resveratrol 3-O-β-D-glucuronide

≥95% (HPLC)

别名:

3-Hydroxy-5-[(1E )-2-(4-hydroxyphenyl)ethenyl]phenyl β-D-glucopyranosiduronic acid, trans-Resveratrol 3-O-glucuronide, trans-Resveratrol 3-glucuronide, RSV 3-O-glucuronide, RSV 3-glucuronide, RSV 3-glur, Resveratrol 3-O-β-D-glucuronide, Resveratrol 3-O-b-D-glucuronide, Resveratrol 3-O-glucuronide, Resveratrol 3-glucuronide

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About This Item

经验公式(希尔记法):
C20H20O9
分子量:
404.37
MDL號碼:
分類程式碼代碼:
12352201
NACRES:
NA.25

生物源

synthetic

品質等級

化驗

≥95% (HPLC)

形狀

solid

分子量

403.37 g/mol

儲存條件

(Tightly closed. Dry)

技術

HPLC: suitable

顏色

white to beige

儲存溫度

2-8°C

SMILES 字串

Canonical SMILES: C1=CC(=CC=C1C=CC2=CC(=CC(=C2)OC3C(C(C(C(O3)C(=O)O)O)O)O)O)OIsomeric SMILES: C1=CC(=CC=C1/C=C/C2=CC(=CC(=C2)O[C@H]3[C@@H]([C@H]([C@@H]([C@H](O3)C(=O)O)O)O)O)O)O

InChI

1S/C20H20O9/c21-12-5-3-10(4-6-12)1-2-11-7-13(22)9-14(8-11)28-20-17(25)15(23)16(24)18(29-20)19(26)27/h1-9,15-18,20-25H,(H,26,27)/b2-1+/t15-,16-,17+,18-,20+/m0/s1

InChI 密鑰

QWSAYEBSTMCFKY-OTPOQTMVSA-N

一般說明

Trans-Resveratrol 3-O-glucuronide, also known as Resveratrol 3-O-glucuronide, is a polyphenol belonging to the stilbenoid glycosides class, found in various plants and fruits. This natural compound is an active metabolite and glucuronide derivative of trans-resveratrol, a polyphenol present in grapes and other plants, known for potential health benefits. Extensive research indicates that it possess diverse biological activities including antioxidant, antiproliferative, anti-inflammatory, and anti-cancer properties. Further, It activates the sirtuin pathway, implicated in aging and metabolism regulation. While its mechanism of action is not fully elucidated, it is believed to engage the sirtuin pathway and inhibit enzymes involved in inflammatory mediator production. Notably, it exhibits inhibitory effects on specific cancer cell proliferation and bacterial growth.Furthermore, it also exerts inhibitory effects on specific cancer cell proliferation and bacterial growth. This active form undergoes various metabolic transformations, including hydrolysis, oxidation, reduction, and glucuronidation, exhibiting frequent interaction with human erythrocytes. Such characteristics make it crucial for biochemical and metabolomics research.

應用

trans-Resveratrol 3-O-β-ᴅ-glucuronide is a metabolite that finds application in metabolomics and biochemical research.

特點和優勢

  • High-purity compound suitable for a wide variety of research applications

其他說明

For additional information on our range of Biochemicals, please complete this form.

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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Susan J Zunino et al.
Oncology letters, 14(2), 2517-2522 (2017-08-07)
Resveratrol has been reported to inhibit or induce DNA damage, depending upon the type of cell and the experimental conditions. Dietary resveratrol is present in the body predominantly as metabolites and limited data is available concerning the activities of these
Ljubica Svilar et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 1104, 119-129 (2018-11-20)
Trans-resveratrol is a stilbene polyphenol with a large spectrum of biological activities. This is why it is widely studied in terms of activities, bioavailability and quantitation in different foods, beverages and biological matrices. Different analytical methods are employed for its

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