PHR3402

阿加曲班 一水合物

• 别名: (2R,4R)-1-[(2S)-5-[（氨基亚氨基甲基）氨基]-1-氧代-2- [[（1,2,3,4-四氢-3-甲基-8-喹啉基）磺酰基] 氨基] 戊基]-4-甲基-2-哌啶羧酸, 精氨酸, 质量受权人
• 经验公式（希尔记法）: C₂₃H₃₆N₆O₅S · H₂O
• CAS号: 141396-28-3
• 分子量: 526.65
• 分類程式碼代碼: 41116107
• NACRES: NA.24

属性

• 等級: certified reference material; pharmaceutical secondary standard
• 品質等級: 300
• agency: traceable to USP 1042408
• CofA: current certificate can be downloaded
• 包裝: pkg of 500 mg
• 應用: pharmaceutical
• 儲存溫度: 2-8°C
• SMILES 字串: [S](=O)(=O)(NC(CCCNC(=N)N)C(=O)N3[C@H](C[C@@H](CC3)C)C(=O)O)c1c2c(ccc1)CC(CN2)C.O
• InChI: 1S/C23H36N6O5S.H2O/c1-14-8-10-29(18(12-14)22(31)32)21(30)17(6-4-9-26-23(24)25)28-35(33,34)19-7-3-5-16-11-15(2)13-27-20(16)19;/h3,5,7,14-15,17-18,27-28H,4,6,8-13H2,1-2H3,(H,31,32)(H4,24,25,26);1H2/t14-,15?,17?,18-;/m1./s1
• InChI 密鑰: AIEZTKLTLCMZIA-LINCPPCXSA-N

说明

一般說明

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards

應用

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

生化／生理作用

阿加曲班是一种强效、选择性、单价凝血酶直接抑制剂。与既结合活性站点又结合外部位点 1 的二价 DTI（水蛭素及其类似物）相比，它只结合凝血酶的活性点位（因此属于单价）而直接抑制凝血酶。

阿加曲班是一种强效、选择性、直接的凝血酶抑制剂，也是一种临床抗凝药。

其他說明

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

安全信息

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable