PHR1464

氨苯砜

Pharmaceutical Secondary Standard; Certified Reference Material

• 别名: 4-氨基苯砜, 4,4'-二氨基二苯砜, 4,4′-磺酰基二苯胺, DDS, 双(4-氨基苯基)砜, 氨苯砜
• 线性分子式: (H₂NC₆H₄)₂SO₂
• CAS号: 80-08-0
• 分子量: 248.30
• Beilstein: 788055
• EC號碼: 201-248-4
• MDL號碼: MFCD00007887
• 分類程式碼代碼: 41116107
• PubChem物質ID: 329823395
• NACRES: NA.24

属性

• 等級: certified reference material; pharmaceutical secondary standard
• 品質等級: 300
• agency: traceable to BP 102; traceable to Ph. Eur. D0100000; traceable to USP 1164008
• API 家族: dapsone
• CofA: current certificate can be downloaded
• 包裝: pkg of 1 g
• 技術: HPLC: suitable; gas chromatography (GC): suitable
• mp: 175-177 °C (lit.)
• 應用: pharmaceutical (small molecule)
• 格式: neat
• 儲存溫度: 2-30°C
• SMILES 字串: Nc1ccc(cc1)S(=O)(=O)c2ccc(N)cc2
• InChI: 1S/C12H12N2O2S/c13-9-1-5-11(6-2-9)17(15,16)12-7-3-10(14)4-8-12/h1-8H,13-14H2
• InChI 密鑰: MQJKPEGWNLWLTK-UHFFFAOYSA-N

说明

一般說明

Dapsone is an antibacterial drug, belongs to a class of compounds known as sulfones. It acts by inhibiting the synthesis of dihydrofolic acid through competition with para-aminobenzoate for the active site of dihydropteroate synthetase, thereby inhibiting the growth of microorganisms that are dependent on endogenous folic acid synthesis. It is used in primary treatment of dermatitis herpetiformis and in combination with other drugs to treat leprosy.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

應用

Dapsone may be used as a pharmaceutical reference standard for the determination of the analyte in bulk drug and pharmaceutical formulations by chromatography.

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

分析報告

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

其他說明

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

腳註

To see an example of a Certificate of Analysis for this material enter LRAA3012 in the slot below. This is an example certificate only and may not be the lot that you receive.

推薦產品

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

安全信息

• 象形圖: GHS07,GHS08,GHS09
• 訊號詞: Danger
• 危險聲明: H302 - H360F - H371 - H373 - H411
• 防範說明: P202 - P260 - P264 - P273 - P301 + P312 - P308 + P311
• 危險分類: Acute Tox. 4 Oral - Aquatic Chronic 2 - Repr. 1B - STOT RE 2 - STOT SE 2
• 標靶器官: Blood
• 儲存類別代碼: 6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable