PHR1129

丁卡因 盐酸盐

Pharmaceutical Secondary Standard; Certified Reference Material

• 别名: 4-(丁氨基)-苯甲酸-2-(二甲氨基)乙酯, 丁卡因 盐酸盐
• 经验公式（希尔记法）: C₁₅H₂₄N₂O₂ · HCl
• CAS号: 136-47-0
• 分子量: 300.82
• MDL號碼: MFCD00038912
• 分類程式碼代碼: 41116107
• PubChem物質ID: 329823150
• NACRES: NA.24

属性

• 等級: certified reference material; pharmaceutical secondary standard
• 品質等級: 300
• agency: traceable to Ph. Eur. T0500000; traceable to USP 1650006
• API 家族: tetracaine
• CofA: current certificate can be downloaded
• 技術: HPLC: suitable; gas chromatography (GC): suitable
• 應用: pharmaceutical (small molecule)
• 格式: neat
• 儲存溫度: 2-30°C
• SMILES 字串: Cl.CCCCNc1ccc(cc1)C(=O)OCCN(C)C
• InChI: 1S/C15H24N2O2.ClH/c1-4-5-10-16-14-8-6-13(7-9-14)15(18)19-12-11-17(2)3;/h6-9,16H,4-5,10-12H2,1-3H3;1H
• InChI 密鑰: PPWHTZKZQNXVAE-UHFFFAOYSA-N
• 基因資訊: human ... SCN10A(6336) , SCN11A(11280) , SCN1A(6323) , SCN2A(6326) , SCN3A(6328) , SCN4A(6329) , SCN5A(6331) , SCN7A(6332) , SCN8A(6334) , SCN9A(6335)

说明

一般說明

Tetracaine hydrochloride is a local anesthetic drug and an ester derivative of p-amino benzoic acid. It acts by interfering with the entry of sodium ions into nerve cells and is one of the commonly used topical anesthetics.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

應用

Tetracaine hydrochloride may be used as a pharmaceutical reference standard for the determination of the analyte in bulk drug and pharmaceutical formulations by high performance liquid chromatography.

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

眼用局部麻醉药；用于脊髓麻醉

生化／生理作用

阻断 Ca²⁺ 从肌浆网的电压敏感性释放。

分析報告

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

其他說明

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

腳註

To see an example of a Certificate of Analysis for this material enter LRAA7150 in the slot below. This is an example certificate only and may not be the lot that you receive.

安全信息

• 象形圖: GHS06
• 訊號詞: Danger
• 危險聲明: H301,H319,H336
• 防範說明: P261 - P264 - P271 - P280 - P301 + P310 - P305 + P351 + P338
• 危險分類: Acute Tox. 3 Oral - Eye Irrit. 2 - STOT SE 3
• 標靶器官: Central nervous system
• 儲存類別代碼: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable