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Merck

PHR1006

Supelco

山梨醇

Pharmaceutical Secondary Standard; Certified Reference Material

别名:

D -山梨醇, D-山梨糖醇

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About This Item

经验公式(希尔记法):
C6H14O6
CAS号:
分子量:
182.17
Beilstein:
1721899
EC號碼:
MDL號碼:
分類程式碼代碼:
12352201
PubChem物質ID:
NACRES:
NA.24

等級

certified reference material
pharmaceutical secondary standard

品質等級

agency

traceable to Ph. Eur. S100000
traceable to USP 1617000

蒸汽密度

<1 (vs air)

蒸汽壓力

<0.1 mmHg ( 25 °C)

API 家族

sorbitol

CofA

current certificate can be downloaded

技術

HPLC: suitable
gas chromatography (GC): suitable

mp

98-100 °C (lit.)

應用

cleaning products
cosmetics
flavors and fragrances
food and beverages
personal care
pharmaceutical (small molecule)

形式

neat

儲存溫度

2-30°C

SMILES 字串

OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)CO

InChI

1S/C6H14O6/c7-1-3(9)5(11)6(12)4(10)2-8/h3-12H,1-2H2/t3-,4+,5-,6-/m1/s1

InChI 密鑰

FBPFZTCFMRRESA-JGWLITMVSA-N

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一般說明

Certified pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to in-house working standards.

應用

山梨醇可用作药物参考标准品,用于通过高效液相色谱法测定药物配方中的分析物。
这些二级标准品是经过检验的认证标准物质(CRM)。它们适用于多种分析应用,包括但不限于药物释放测试、药物的定性和定量分析方法开发、食品和饮料质量控制检测以及其他标定应用。
采用气相色谱法 (GLC) 定量测定玉米糖和玉米糖浆中的 D-葡萄糖时,山梨醇可作为内标物。

分析報告

这些二级标准品可多次溯源至美国药典、欧洲药典和英国药典一级标准品(如可用)。

其他說明

该认证标准物质(CRM)根据ISO 17034ISO/IEC 17025进行生产和认证。有关此CRM使用的所有信息均可在分析证书上找到。

腳註

如需查看该材料的检验报告示例,请在下面的栏位中输入 LRAB7795。这只是一个示例证书,可能不是您收到的批次。

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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An isocratic HPLC method for the determination of sorbitol and glycerol in pharmaceutical formulations
Simonzadeh N and Ronsen B
Journal of Chromatographic Science, 50(7), 644-647 (2012)
Use of sorbitol as internal standard in determination of D-glucose by gas liquid chromatography
Alexander.J.R and Garbutt.T.J
Analytical Chemistry, 37, 303-305 (1965)
Determination of nimesulide in pharmaceutical dosage forms by second order derivative UV spectrophotometry
Altinoz S and Dursun OO
Journal of Pharmaceutical and Biomedical Analysis, 22(1), 175-182 (2000)
Arlene E Dent et al.
PloS one, 3(10), e3557-e3557 (2008-10-30)
Antibodies that impair Plasmodium falciparum merozoite invasion and intraerythrocytic development are one of several mechanisms that mediate naturally acquired immunity to malaria. Attempts to correlate anti-malaria antibodies with risk of infection and morbidity have yielded inconsistent results. Growth inhibition assays
Anna Boccaccio et al.
Cellular and molecular life sciences : CMLS, 71(21), 4275-4283 (2014-04-29)
Two-pore channel proteins (TPC) encode intracellular ion channels in both animals and plants. In mammalian cells, the two isoforms (TPC1 and TPC2) localize to the endo-lysosomal compartment, whereas the plant TPC1 protein is targeted to the membrane surrounding the large

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