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Merck
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主要文件

O0146000

Olsalazine sodium

European Pharmacopoeia (EP) Reference Standard

别名:

4,4′-Dihydroxyazobenzene-3,3′-dicarboxylic acid disodium salt, 5,5′-Azobis(salicylic acid, sodium salt), Mordant Yellow 5

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About This Item

经验公式(希尔记法):
C14H8N2Na2O6
CAS号:
分子量:
346.20
分類程式碼代碼:
41116107
NACRES:
NA.24

等級

pharmaceutical primary standard

API 家族

olsalazine

製造商/商標名

EDQM

應用

pharmaceutical (small molecule)

形式

neat

儲存溫度

2-8°C

InChI

1S/C14H10N2O6.2Na/c17-11-3-1-7(5-9(11)13(19)20)15-16-8-2-4-12(18)10(6-8)14(21)22;;/h1-6,15,17H,(H,19,20)(H,21,22);;/q;2*+1/p-2/b16-8-;;

InChI 密鑰

QQWFSVYVHLECFP-XBPUGJBTSA-L

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一般說明

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

應用

Olsalazine sodium EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

包裝

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

其他說明

Sales restrictions may apply.

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B Nigović et al.
Die Pharmazie, 57(7), 468-470 (2002-08-10)
The electrochemical behavior of 2-hydroxy-5-[(4-sulfophenyl)azo]benzoic acid, 2-hydroxy-5-[(3-sulfophenyl)azo]benzoic acid and 2-hydroxy-5-[(2-sulfophenyl)-azo]benzoic acid was investigated by cyclic voltammetry using a glassy carbon electrode. The influence of the pH and position of the substituents on the reaction pathway has been studied. The results
Lutz Buschhausen et al.
Medizinische Klinik (Munich, Germany : 1983), 101(10), 791-795 (2006-10-14)
Patients with ulcerative colitis have a higher rate of tubular nephropathies. Data concerning the cause of these lesions is rare and inconsistent, the occurrence may be part of the disease itself or a side effect of 5-aminosalicylates (5-ASA). This study
Yue-Meng Wan et al.
The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology, 22(5), 486-493 (2012-01-12)
We aimed to investigate the therapeutic effects of Peifeikang, a probiotics compound, on colitis in rats induced by trinitrobenzene sulfonic acid and to elucidate its potential mechanism. We evaluated the therapeutic effects of Peifeikang by analysis of the disease activity
Xue-Liang Jiang et al.
World journal of gastroenterology, 10(10), 1513-1520 (2004-05-11)
To study the different therapy for different types of ulcerative colitis (UC) in China. Among 102 UC patients, 42 chronic relapse type UC patients were randomly divided into olsalazine sodium treatment group (n=21) and SASP group (n=21). Clinical effects and
Kersti Oselin et al.
Drug metabolism and disposition: the biological fate of chemicals, 35(9), 1452-1454 (2007-06-08)
Thiopurine S-methyltransferase (TPMT) is a biotransformation phase II enzyme responsible for the metabolic inactivation of thiopurine drugs. The present study was carried out to investigate the inhibitory potential of 15 nonsteroidal anti-inflammatory drugs (NSAIDs) on human TPMT activity in vitro.

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