I7905

布洛芬

meets USP testing specifications

• 别名: α-甲基-4-(异丁基)苯乙酸, (±)-2-(4-异丁基苯基)丙酸
• 经验公式（希尔记法）: C₁₃H₁₈O₂
• CAS号: 15687-27-1
• 分子量: 206.28
• EC號碼: 239-784-6
• MDL號碼: MFCD00010393
• 分類程式碼代碼: 12352106
• PubChem物質ID: 24896130
• NACRES: NA.21

属性

• agency: USP/NF; meets USP testing specifications
• 品質等級: 200
• 形狀: solid
• 應用: pharmaceutical (small molecule)
• SMILES 字串: CC(C)Cc1ccc(cc1)C(C)C(O)=O
• InChI: 1S/C13H18O2/c1-9(2)8-11-4-6-12(7-5-11)10(3)13(14)15/h4-7,9-10H,8H2,1-3H3,(H,14,15)
• InChI 密鑰: HEFNNWSXXWATRW-UHFFFAOYSA-N
• 基因資訊: human ... ALB(213) , ALOX5(240) , CYP1A2(1544) , CYP2C9(1559) , IL8RA(3577) , PTGS1(5742) , PTGS2(5743) ; mouse ... Alox5(11689) ; rat ... Alox5(25290) , Ptgs1(24693)

说明

應用

• A Case of Erythema Nodosum in a 20-Year-Old Female During the Postpartum Period.: Details a clinical case where ibuprofen was implicated in the treatment of erythema nodosum, offering insights into its therapeutic applications and associated risks (Nguyen M et al., 2024).


• Coracoclavicular Joint Arthrosis - An Uncommon Cause of Shoulder Pain.: Investigates the use of ibuprofen in managing pain associated with rare joint disorders, contributing to broader understanding of pain management in orthopedic conditions (Graça NNJ et al., 2024).

生化／生理作用

环加氧酶 (COX) 抑制剂，对 COX-1 的抑制活性大于对 COX-2 的抑制活性。

安全信息

• 象形圖: GHS07
• 訊號詞: Warning
• 危險聲明: H302,H319,H335
• 防範說明: P261 - P264 - P271 - P280 - P301 + P312 - P305 + P351 + P338
• 危險分類: Acute Tox. 4 Oral - Eye Irrit. 2 - STOT SE 3
• 標靶器官: Respiratory system
• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 1
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable
• 個人防護裝備: dust mask type N95 (US), Eyeshields, Gloves