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Merck

I2399

Sigma-Aldrich

咪唑

ACS reagent, ≥99% (titration)

别名:

1,3-二氮杂-2,4-环戊二烯, 甘恶啉

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About This Item

经验公式(希尔记法):
C3H4N2
CAS号:
分子量:
68.08
Beilstein:
103853
EC號碼:
MDL號碼:
分類程式碼代碼:
12352005
eCl@ss:
39161001
PubChem物質ID:
NACRES:
NA.21

等級

ACS reagent

品質等級

蒸汽壓力

<1 mmHg ( 20 °C)

化驗

≥99% (titration)

雜質

≤0.2% water

燃燒殘留物

≤0.1%

pH值

9.5-11.0 (25 °C, 5% in H2O)

pKa (25 °C)

6.95

bp

256 °C (lit.)

mp

88-91 °C (lit.)

正離子痕跡

Fe: ≤0.001%

SMILES 字串

c1c[nH]cn1

InChI

1S/C3H4N2/c1-2-5-3-4-1/h1-3H,(H,4,5)

InChI 密鑰

RAXXELZNTBOGNW-UHFFFAOYSA-N

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一般說明

咪唑是一种五元杂环化合物,存在于许多天然化合物中。它兼有酸性和碱性特性。据报道,它是血栓形成的抑制剂。其垂直谱和无辐射衰减已得到记录和分析。

應用

特别适用于 pH 6.2-7.8 范围内的缓冲液

法律資訊

Redi-Dri is a trademark of Sigma-Aldrich Co. LLC

訊號詞

Danger

危險聲明

危險分類

Acute Tox. 4 Oral - Eye Dam. 1 - Repr. 1B - Skin Corr. 1C

儲存類別代碼

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

水污染物質分類(WGK)

WGK 2

閃點(°F)

293.0 °F - closed cup

閃點(°C)

145 °C - closed cup

個人防護裝備

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges


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分析证书(COA)

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UV excitation and radiationless deactivation of imidazole.
Barbatti M, et al.
J. Chem. Phys., 130(3), 034305-034305 (2009)
Zhong Jin
Natural product reports, 28(6), 1143-1191 (2011-04-08)
A great number of structurally diverse natural products containing five-membered heterocyclic subunits, such as imidazole, oxazole, thiazole, and their saturated congeners, are abundant in nature. These naturally occurring metabolites often exhibit extensive and pharmacologically important biological activities. The latest progress
S Moncada et al.
Prostaglandins, 13(4), 611-618 (1977-04-01)
Imidazole inhibits the enzymic conversion of the endoperoxides (PGG2 and PGH2) to thromboxane A2 by platelet microsomes (IC50: 22 MICRONG/ML; DETERMINED BY BIOASSAY). The inhibitor is selective, for prostaglandin cyclo-oxygenase is only affected at high doses. Radiochemical data confirms that
Peter Canning et al.
Journal of molecular biology, 426(13), 2457-2470 (2014-04-29)
The discoidin domain receptors (DDRs), DDR1 and DDR2, form a unique subfamily of receptor tyrosine kinases that are activated by the binding of triple-helical collagen. Excessive signaling by DDR1 and DDR2 has been linked to the progression of various human
Pam M Van Ry et al.
Molecular therapy : the journal of the American Society of Gene Therapy, 23(8), 1285-1297 (2015-06-09)
Duchenne muscular dystrophy (DMD) is a fatal neuromuscular disease caused by mutations in the dystrophin gene, leading to the loss of a critical component of the sarcolemmal dystrophin glycoprotein complex. Galectin-1 is a small 14 kDa protein normally found in skeletal

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