推荐产品
生物源
synthetic
品質等級
化驗
≥97% (titration)
形狀
powder or crystals
技術
RNA extraction: suitable
顏色
white to off-white
mp
120-122 °C (lit.)
溶解度
water: 4 M, clear, colorless
負離子痕跡
chloride (Cl-): ≤2.5%
SMILES 字串
SC#N.NC(N)=N
InChI
1S/CH5N3.CHNS/c2-1(3)4;2-1-3/h(H5,2,3,4);3H
InChI 密鑰
ZJYYHGLJYGJLLN-UHFFFAOYSA-N
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應用
硫氰酸胍可用于：
- 用作变性剂研究其对球状蛋白表面活性的影响
- 从原代肝细胞提取总核糖核酸(RNA)
- 用作从人骨中提取DNA的培养缓冲液组分
- 用作提取象鼻鲨的DNA的硫氰酸胍(GITC)裂解缓冲液组分
- 用作从大鼠胰腺组织提取RNA的裂解液组分
离液剂和强效变性剂;溶解细胞。
生化／生理作用
硫氰酸胍(GTC)是一种强效蛋白质变性剂，能够变性内源性核糖核酸酶。它在从核糖体中分离核蛋白体核糖核酸(rRNA)方面起着重要作用。GTC可与苯酚、氯仿联用，从细胞和组织中分离总核糖核酸。
訊號詞
Danger
危險分類
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Dam. 1 - Skin Corr. 1C
安全危害
儲存類別代碼
8B - Non-combustible corrosive hazardous materials
水污染物質分類（WGK）
WGK 2
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
dust mask type N95 (US), Eyeshields, Gloves
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Transforming growth factor beta (TGFβ) acts either as a tumor suppressor or as an oncogene, depending on the cellular context and time of activation. TGFβ activates the canonical SMAD pathway through its interaction with the serine/threonine kinase type I and II
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Angiotensin converting enzyme 2 (ACE2) which breaks down profibrotic peptide angiotensin II to antifibrotic peptide angiotensin-(1-7) is a potential therapeutic target in liver fibrosis. We therefore investigated the long-term therapeutic effect of recombinant ACE2 using a liver-specific adeno-associated viral genome
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High-quality total RNA was extracted using a cethyltrimethylammonium bromide-containing buffer followed by an acid guanidium thiocyanate-phenol-chloroform treatment from recalcitrant plant tissues such as tree leaves (pine, Norway spruce, ginkgo, Japanese cedar, rose), flowers (rose, Lotus japonicus) and storage tissues (seeds
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