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Merck

F0040000

芬苯达唑

European Pharmacopoeia (EP) Reference Standard

别名:

5-苯硫基苯并咪唑-2-氨基甲酸甲酯

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About This Item

经验公式(希尔记法):
C15H13N3O2S
CAS号:
分子量:
299.35
Beilstein:
759077
MDL號碼:
分類程式碼代碼:
41116107
PubChem物質ID:
NACRES:
NA.24

等級

pharmaceutical primary standard

API 家族

fenbendazole

製造商/商標名

EDQM

應用

pharmaceutical (small molecule)

格式

neat

儲存溫度

2-8°C

SMILES 字串

COC(=O)Nc1nc2cc(Sc3ccccc3)ccc2[nH]1

InChI

1S/C15H13N3O2S/c1-20-15(19)18-14-16-12-8-7-11(9-13(12)17-14)21-10-5-3-2-4-6-10/h2-9H,1H3,(H2,16,17,18,19)

InChI 密鑰

HDDSHPAODJUKPD-UHFFFAOYSA-N

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一般說明

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

應用

Fenbendazole EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

包裝

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

其他說明

Sales restrictions may apply.

象形圖

Health hazardEnvironment

訊號詞

Warning

危險聲明

危險分類

Aquatic Acute 1 - Aquatic Chronic 1 - Repr. 2 - STOT RE 2

標靶器官

Liver,lymph node,Stomach,Nervous system

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3


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分析证书(COA)

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David Villar et al.
Journal of the American Association for Laboratory Animal Science : JAALAS, 46(6), 8-15 (2007-11-13)
This review summarizes findings from toxicologic, carcinogenic, immunologic, and metabolic studies on fenbendazole (FBZ). Currently, FBZ is used to treat or prevent pinworm outbreaks in laboratory rodents. Because antiparasitic treatments usually are not part of experimental designs, interactions from the
Vanessa O Ezenwa et al.
Science (New York, N.Y.), 347(6218), 175-177 (2015-01-13)
Parasitic worms modulate host immune responses in ways that affect microbial co-infections. For this reason, anthelmintic therapy may be a potent tool for indirectly controlling microbial pathogens. However, the population-level consequences of this type of intervention on co-infecting microbes are
Bettencourt P S Capece et al.
Veterinary journal (London, England : 1997), 181(3), 241-250 (2009-01-07)
Albendazole and fenbendazole are methylcarbamate benzimidazole anthelmintics extensively used to control gastrointestinal parasites in domestic animals. These parent compounds are metabolised to albendazole sulfoxide and fenbendazole sulfoxide (oxfendazole), respectively. Both sulfoxide derivatives are anthelmintically active and are manufactured for use
Xiao-Lin Hou et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 962, 20-29 (2014-06-03)
A simple, sensitive and reliable analytical method was developed for the simultaneous determination of 38 veterinary drugs (18 sulfonamides, 11 quinolones and 9 benzimidazoles) and 8 metabolites of benzimidazoles in bovine milk by ultra high performance liquid chromatography-positive electrospray ionization

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