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Merck

C0470000

羧甲司坦

European Pharmacopoeia (EP) Reference Standard

别名:

S-羧甲基-L-半胱氨酸, 3-羧甲基硫代-L-丙氨酸

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About This Item

经验公式(希尔记法):
C5H9NO4S
CAS号:
分子量:
179.19
Beilstein:
1725012
MDL號碼:
分類程式碼代碼:
41116107
PubChem物質ID:
NACRES:
NA.24

等級

pharmaceutical primary standard

API 家族

carbocisteine

製造商/商標名

EDQM

應用

pharmaceutical (small molecule)

格式

neat

SMILES 字串

N[C@@H](CSCC(O)=O)C(O)=O

InChI

1S/C5H9NO4S/c6-3(5(9)10)1-11-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10)/t3-/m0/s1

InChI 密鑰

GBFLZEXEOZUWRN-VKHMYHEASA-N

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一般說明

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

應用

Carbocisteine EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

包裝

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

其他說明

Sales restrictions may apply.

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 2

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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分析证书(COA)

Lot/Batch Number

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Li Sun et al.
Respirology (Carlton, Vic.), 15(7), 1064-1071 (2010-09-03)
Carbocysteine (S-carboxymethylcysteine) is a mucoactive drug with in vitro free radical scavenging and anti-inflammatory properties. Several clinical trials have indicated that carbocysteine reduces exacerbation rates in COPD. In the present study, the effect of carbocysteine on the airway load of
Masanori Asada et al.
Respiratory physiology & neurobiology, 180(1), 112-118 (2011-11-15)
To examine the effects of l-carbocisteine on airway infection with respiratory syncytial (RS) virus, human tracheal epithelial cells were pretreated with l-carbocisteine and infected with RS virus. Viral titer, virus RNA, and pro-inflammatory cytokine secretion, including interleukin (IL)-1 and IL-6
Yuichi Majima et al.
Auris, nasus, larynx, 39(1), 38-47 (2011-06-04)
In Japan, fourteen-membered ring macrolides, antibacterial agents, and S-carboxymethylcysteine (SCMC; carbocisteine), a mucolytic, are commonly used to treat chronic rhinosinusitis (CRS), and they are also used in combination. However, no large-scale randomized study has examined the effects of these pharmacotherapies.
Kenichiro Kudo et al.
Internal medicine (Tokyo, Japan), 52(1), 97-100 (2013-01-08)
A 32-year-old male with CATCH22 syndrome presented with a high fever and productive cough after taking drugs for acute bronchitis, including (L)-carbocisteine. Chest radiography revealed ground-glass opacities in the bilateral lung fields. He had a history of similar pneumonia. Under
Drug fever due to S-carboxymethyl-L-cystein: demonstration of a causative agent with patch tests.
Mayumi Hatakeyama et al.
The Journal of dermatology, 39(6), 555-556 (2011-09-29)

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