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About This Item
经验公式（希尔记法）:
C6H10N2O2
CAS号:
分子量:
142.16
Beilstein:
7288977
EC號碼:
MDL號碼:
分類程式碼代碼:
24112111
PubChem物質ID:
NACRES:
NA.21
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品質等級
化驗
≥95.0% (HPLC)
形狀
powder
分子量
142.16 g/mol
儲存條件
dry at room temperature
顏色
white
溶解度
methanol: soluble 10 mg/mL, clear, colorless to almost colorless
SMILES 字串
CC1=N[C@@H](CCN1)C(O)=O
InChI
1S/C6H10N2O2/c1-4-7-3-2-5(8-4)6(9)10/h5H,2-3H2,1H3,(H,7,8)(H,9,10)/t5-/m0/s1
InChI 密鑰
WQXNXVUDBPYKBA-YFKPBYRVSA-N
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一般說明
四氢嘧啶(Ectoine)， 全称4,5,6-四氢-2-甲基-4-嘧啶羧酸， 是一种两性氨基酸衍生物，作为相容性渗透保护溶质， 由好氧型、化能异养型和嗜盐性细菌生产， 抵抗渗透压胁迫、辐射和其他不利的 环境条件。
應用
该 四氢嘧啶的实际应用包括酶稳定、 抗炎处理、神经退行性疾病预防和其他 治疗用途。
生化／生理作用
四氢嘧啶可用作酶稳定剂，在温度变化下维持水化和减少酶变性。还可提高双链DNA的高温稳定性。
其他說明
酶和生物大分子的稳定剂
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 1
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
dust mask type N95 (US), Eyeshields, Gloves
其他客户在看
Jens Smiatek et al.
Biophysical chemistry, 160(1), 62-68 (2011-10-22)
We have performed Molecular Dynamics simulations of ectoine, hydroxyectoine and urea in explicit solvent. Special attention has been spent on the local surrounding structure of water molecules. Our results indicate that ectoine and hydroxyectoine are able to accumulate more water
K. Lippert, E.A. Galinski
Applied Microbiology and Biotechnology, 37, 61-61 (1992)
Ruediger Graf et al.
Clinics in dermatology, 26(4), 326-333 (2008-08-12)
The protective properties of ectoine, formerly described for only extremophilic microorganisms, can be transferred to human skin. Our present data show that the compatible solute ectoine protects the cellular membrane from damage caused by surfactants. Transepidermal water loss measurements in
Ralf Spindler et al.
Cryobiology, 64(3), 250-260 (2012-02-22)
Cellular response during the freeze-thaw process strongly affects the cryopreservation outcome including cell morphology and cell viability. Cryomicroscopy was used to individually analyze the osmotic response of human pulmonary microvascular endothelial cells (HPMECs) during slow cooling (1 °C/min) to -60
Naomi Ofer et al.
Applied and environmental microbiology, 78(20), 7483-7486 (2012-08-14)
Mycobacterium smegmatis is a commonly used mycobacterial model system. Here, we show that M. smegmatis protects itself against elevated salinity by synthesizing ectoine and hydroxyectoine and characterize the phenotype of a nonproducing mutant. This is the first analysis of M.
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