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Merck

62862

Sigma-Aldrich

十二烷基硫酸钠

≥90% ((Assay))

别名:

SDS, 十二烷基硫酸盐 钠盐, 十二烷基硫酸钠, 月桂基硫酸盐 钠盐, 月桂基硫酸钠

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About This Item

线性分子式:
CH3(CH2)11OSO3Na
CAS号:
分子量:
288.38
Beilstein:
3599286
EC號碼:
MDL號碼:
分類程式碼代碼:
12161900
eCl@ss:
39093306
PubChem物質ID:
NACRES:
NA.21

描述

anionic
62

品質等級

化驗

≥90% ((Assay))

分子量

288.38 g/mol

技術

LC/MS: suitable
electrophoresis: suitable
protein quantification: suitable

mp

204-207 °C (lit.)

溶解度

water: soluble

HLB

40

SMILES 字串

[Na+].CCCCCCCCCCCCOS([O-])(=O)=O

InChI

1S/C12H26O4S.Na/c1-2-3-4-5-6-7-8-9-10-11-12-16-17(13,14)15;/h2-12H2,1H3,(H,13,14,15);/q;+1/p-1

InChI 密鑰

DBMJMQXJHONAFJ-UHFFFAOYSA-M

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一般說明

十二烷基硫酸钠(SDS)也称月桂基硫酸钠(SLS),具有一个连接硫酸盐基团、含有12个碳原子的烷基尾。由于硫酸盐基团带负电荷,它是一种阴离子表面活性剂。

應用

十二烷基硫酸钠已用于:

  • 制备用于涂覆Janus 微马达的壳聚糖,以合成镁((Mg)基微马达
  • 作为低盐裂解缓冲液的成分用于裂解’食用燕窝(EBN)处理细胞进行蛋白质印迹分析
  • 制备脱细胞溶液用于减少并脱除皮肤碎片的细胞
阴离子洗涤剂

生化/生理作用

十二烷基硫酸钠(SDS)常被用作各种产品的成分,包括药物和产品制剂。它被广泛用于多种应用,包括蛋白质的电泳分离,也可用作制备周期性介孔有机硅(periodic mesoporous organosilica)纳米球的有机模板。SDS也用于蛋白质和脂质以及药物的增溶,功能化碳纳米管和石墨烯片的分散,气体水合物的形成。它常用于生物膜的快速裂解。由于其能够裂解组织结构,SDS是多种核酸纯化试剂的首选成分。SDS在高盐和离液(chaotropic )溶液中的溶解度非常低,在钾盐中容易沉淀,因此胍盐缓冲液中通常不添加SDS。

特點和優勢

  • 含量测定:≥90%
  • 适用于液相色谱/质谱、电泳和蛋白质定量
  • 抑制RNA酶和DNA酶活性

訊號詞

Danger

危險分類

Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Dam. 1 - Flam. Sol. 2 - Skin Irrit. 2 - STOT SE 3

標靶器官

Respiratory system

儲存類別代碼

4.1B - Flammable solid hazardous materials

水污染物質分類(WGK)

WGK 2

閃點(°F)

338.0 °F

閃點(°C)

170 °C

個人防護裝備

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges


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