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Merck

32138

Supelco

Doripenem monohydrate

VETRANAL®, analytical standard

别名:

(4R,5S,6S)-6-[(1R)-1-Hydroxyethyl]-4-methyl-7-oxo-3-[(3S,5S)-5-[(sulfamoylamino)methyl]pyrrolidin-3-yl]sulfanyl-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid

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About This Item

经验公式(希尔记法):
C15H24N4O6S2 · H2O
分子量:
438.52
Beilstein:
15340136
MDL號碼:
分類程式碼代碼:
41116107
PubChem物質ID:
NACRES:
NA.24

等級

analytical standard

品質等級

產品線

VETRANAL®

技術

HPLC: suitable
gas chromatography (GC): suitable

應用

forensics and toxicology
veterinary

格式

neat

儲存溫度

2-8°C

SMILES 字串

[H]O[H].NS(NC[C@H](C1)NC[C@H]1SC2=C(C(O)=O)N3C([C@]([H])([C@H](O)C)[C@@]3([H])[C@H]2C)=O)(=O)=O

InChI

1S/C15H24N4O6S2.H2O/c1-6-11-10(7(2)20)14(21)19(11)12(15(22)23)13(6)26-9-3-8(17-5-9)4-18-27(16,24)25;/h6-11,17-18,20H,3-5H2,1-2H3,(H,22,23)(H2,16,24,25);1H2/t6-,7-,8+,9+,10-,11-;/m1./s1

InChI 密鑰

NTUBEBXBDGKBTJ-WGLOMNHJSA-N

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一般說明

Doripenem belongs to the carbapenems family of β-lactam antibiotic compounds.

應用

Doripenem monohydrate can be used as the precursor for the preparation of doripenem which may be used as an analytical reference standard for the determination of doripenem in:
  • Bovine muscle by liquid chromatography combined with tandem mass spectrometry (LC-MS/MS).
  • Bulk drug and formulations by high performance thin layer chromatography (HPTLC).
  • Medicinal products by capillary electrophoresis coupled to ultraviolet (UV) detector as well as micellar electrokinetic chromatography (MEKC) with UV detection.

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

法律資訊

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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分析证书(COA)

Lot/Batch Number

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其他客户在看

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Determination of biapenem in a medicinal product by micellar electrokinetic chromatography with sweeping in an enhanced electric field.
Michalska K, et al.
Journal of Chromatography A, 1282(4), 153-160 (2013)
Determination of doripenem and related substances in medicinal product using capillary electrophoresis.
Michalska K, et al.
Journal of Separation Science, 34(4), 475-482 (2011)
A validated HPTLC method for the determination of doripenem in pharmaceutical dosage forms.
Kurien J, et al.
International Journal of Pharmaceutical Sciences Review and Research, 27, 317-321 (2014)
M Di Rocco et al.
Journal of chromatography. A, 1500, 121-135 (2017-04-30)
A method was developed for the confirmatory and quantitative analysis of 30 β-lactam antibiotic residues in bovine muscle. The method includes 12 penicillins (amoxicillin, ampicillin, cloxacillin, dicloxacillin, mecillinam, methicillin, nafcillin, oxacillin, penicillin G, penicillin V, piperacillin, ticarcillin), 12 cephalosporins (cefacetrile

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