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Merck

32002

Sigma-Aldrich

5,5-二乙基巴比土酸钠盐

purum, ≥99.0% (NT)

别名:

5,5-二乙基巴比土酸 钠盐, 佛罗拿 钠盐, 巴比妥, 巴比妥钠

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About This Item

经验公式(希尔记法):
C8H11N2NaO3
CAS号:
分子量:
206.17
Beilstein:
3921202
EC號碼:
MDL號碼:
分類程式碼代碼:
12161703
PubChem物質ID:
NACRES:
NA.77

等級

purum

品質等級

化驗

≥99.0% (NT)

形狀

powder or crystals

藥物控制

regulated under CDSA - not available from Sigma-Aldrich Canada; psicótropo (Spain); Decreto Lei 15/93: Tabela IV (Portugal)

儲存條件

(Tightly closed. Dry.)

技術

GC/MS: suitable
HPLC: suitable
activity assay: suitable

顏色

colorless

pH值

9.0-10.5

mp

>287.1 °C (> 548.8 °F)

溶解度

water: soluble 103.1 g/L at 20 °C (68 °F)

密度

1.418 g/cm3 at 20 °C ( 68 °F)

適合性

suitable for microbiology
suitable for molecular biology

應用

cell analysis

SMILES 字串

[Na+].CCC1(CC)C(=O)NC([O-])=NC1=O

InChI

1S/C8H12N2O3.Na/c1-3-8(4-2)5(11)9-7(13)10-6(8)12;/h3-4H2,1-2H3,(H2,9,10,11,12,13);/q;+1/p-1

InChI 密鑰

RGHFKWPGWBFQLN-UHFFFAOYSA-M

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一般說明

Sodium 5,5-diethyl barbiturate, also known as Barbital sodium, is a long-acting barbiturate that can significantly depress various metabolic processes at high doses. This weak acid has widespread applications in scientific fields, particularly as a buffering solution in biochemical and biological experiments due to its buffering capabilities. It is particularly well-suited for scenarios requiring lower buffer capacity without compromising pH stability. This buffering effect is achieved through the equilibrium between the acid and its corresponding anion, effectively stabilizing the pH within the desired range. Additionally, Sodium 5,5-diethyl barbiturate has potential applications in histology, and biochemical research, including uses in enzyme assays, cell structure staining, and electrophoresis.

應用

Sodium 5,5-diethyl barbiturate has been used as a component of Michaeli′s buffer, a commonly used buffer solution that helps maintain ideal conditions for histological and histopathological analyses. It is also utilized as a biological buffer in immunoelectrophoresis, hemolytic assays and fixative solutions.

生化/生理作用

镇静/催眠

特點和優勢

  • Suitable for electrophoresis and enzymatic assays
  • High purity product for research applications
  • Component of Michaeli′s buffer

警告

Substance of abuse. Regulatory approval may be required for purchase. Comply with applicable laws. Exercise responsible use.

其他說明

For additional information on our range of Biochemicals, please complete this form.
This product is intended for research purposes only, and it is not meant for human consumption.
可能实行销售限制

同類產品

象形圖

Health hazardExclamation mark

訊號詞

Warning

危險分類

Acute Tox. 4 Oral - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT SE 2 - STOT SE 3

標靶器官

Nervous system, Respiratory system

儲存類別代碼

13 - Non Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

dust mask type N95 (US), Eyeshields, Faceshields, Gloves


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C S Rinder et al.
The Journal of clinical investigation, 96(3), 1564-1572 (1995-09-01)
Complement activation contributes to the systemic inflammatory response induced by cardiopulmonary bypass. At the cellular level, cardiopulmonary bypass activates leukocytes and platelets; however the contribution of early (3a) versus late (C5a, soluble C5b-9) complement components to this activation is unclear.
Y Hiasa et al.
Carcinogenesis, 3(10), 1187-1190 (1982-01-01)
Phenobarbital (PB) and barbital (BB) promoted the development of thyroid tumors in rats treated with a sub-effective dose of N-bis(2-hydroxypropyl)nitrosamine (DHPN) for thyroid tumorigenesis. Rats were given s.c. injections of 70 mg DHPN/100 g body weight once a week for

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