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等級
analytical standard
品質等級
產品線
VETRANAL®
儲存期限
limited shelf life, expiry date on the label
技術
HPLC: suitable
gas chromatography (GC): suitable
應用
clinical testing
形式
neat
儲存溫度
2-8°C
SMILES 字串
COc1ncnc(NS(=O)(=O)c2ccc(N)cc2)c1OC
InChI
1S/C12H14N4O4S/c1-19-10-11(14-7-15-12(10)20-2)16-21(17,18)9-5-3-8(13)4-6-9/h3-7H,13H2,1-2H3,(H,14,15,16)
InChI 密鑰
PJSFRIWCGOHTNF-UHFFFAOYSA-N
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一般說明
Chemical structure: sulfonamide
Sulfadoxin belongs to the long acting group of sulfonamides, which acts by inhibiting dihydropteroate synthase in intracellular sporozoa such as Eimeria and Toxoplasma and Plasmodium.
應用
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Sulfadoxin may be used as a reference standard for the determination of the analyte in plasma samples using packed-column supercritical fluid chromatography (SFC).
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Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
法律資訊
VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany
訊號詞
Warning
危險聲明
危險分類
Aquatic Chronic 2 - Skin Sens. 1
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 2
個人防護裝備
dust mask type N95 (US), Eyeshields, Gloves
其他客户在看
Determination of sulfadoxine in human blood plasma using packed-column supercritical fluid chromatography.
Bhoir IS, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 757(1) (2001)
Encyclopedic Reference of Parasitology, 2(2) (2001)
Arti Basra et al.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 56(6), e68-e75 (2012-11-24)
Urogenital schistosomiasis is a major public health problem in sub-Saharan Africa, and routine programs for screening and treatment of pregnant women are not established. Mefloquine-currently evaluated as a potential alternative to sulfadoxine-pyrimethamine as intermittent preventive treatment against malaria in pregnancy
Alexia Daoust et al.
NeuroImage, 96, 133-142 (2014-04-08)
The MAP6 (microtubule-associated protein 6) KO mouse is a microtubule-deficient model of schizophrenia that exhibits severe behavioral disorders that are associated with synaptic plasticity anomalies. These defects are alleviated not only by neuroleptics, which are the gold standard molecules for
Inbarani Naidoo et al.
Trends in parasitology, 29(10), 505-515 (2013-09-14)
Sulfadoxine-pyrimethamine (SP) is used throughout Africa for intermittent preventive treatment (IPT) of malaria, but resistance threatens its efficacy. We found marked regional differences in the genotypes responsible for SP resistance when mapping recent surveys of dihydrofolate reductase (dhfr) and dihydropteroate
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