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Merck

235989

Sigma-Aldrich

Brij® L4聚氧乙烯月桂醚

average Mn ~362

别名:

四聚乙二醇单月桂醚, 聚氧乙烯 (4) 月桂醚

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About This Item

线性分子式:
(C20H42O5)n
CAS号:
MDL號碼:
分類程式碼代碼:
12161900
PubChem物質ID:
NACRES:
NA.21

描述

non-ionic

品質等級

分子量

average Mn ~362

折射率

n20/D 1.451 (lit.)

密度

0.95 g/mL at 25 °C (lit.)

HLB

9

SMILES 字串

CCCCCCCCCCCCOCCOCCOCCOCCO

InChI

1S/C20H42O5/c1-2-3-4-5-6-7-8-9-10-11-13-22-15-17-24-19-20-25-18-16-23-14-12-21/h21H,2-20H2,1H3

InChI 密鑰

WPMWEFXCIYCJSA-UHFFFAOYSA-N

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一般說明

Brij® L4 是一种非离子表面活性剂。它含有一个连接氧乙烯基头基的烷基(C12)尾。

應用

Brij® L4 已被用于:
  • 作为表面活性剂采用微乳液技术合成氧化铜(I)(Cu2O) 球形纳米颗粒
  • 作为非离子表面活性剂用于制备反胶束以合成Pt3Co 合金纳米颗粒
  • 作为表面活性剂用于改善疏水材料界面偶联的效率并生成水凝胶

生化/生理作用

Brij® L4 具有两亲性。Brij L4 含有疏水和亲水区域,可以形成胶束并使疏水药物分散进入胶束核中。这相应地改善了药物的溶解性。Brij L4也对乳腺癌耐药蛋白(BCRP)介导的药物外排有强烈的抑制作用。与其它常用表面活性剂相比,它对Taq吸附的抑制作用更强。Brij L4 有助于在标准Taq浓度下进行皮升反应体积的液滴聚合酶链式反应(PCR)。

法律資訊

Brij is a registered trademark of Croda International PLC

象形圖

Exclamation markEnvironment

訊號詞

Warning

危險分類

Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Irrit. 2 - Skin Irrit. 2

儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 2

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves


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Darío Morais et al.
Rhinology, 50(1), 80-86 (2012-04-04)
Hereditary Haemorrhagic Telangiectasia or Rendu-Osler-Weber syndrome is a rare autosomal dominant vascular disease characterized by mucocutaneous and gastrointestinal telangiectases and localized arteriovenous malformations in lung, brain and liver. Epistaxis, due to rupture of telangiectases of the nasal mucosa, is the
N Shadid et al.
The British journal of surgery, 99(8), 1062-1070 (2012-05-26)
New minimally invasive treatment modalities, such as ultrasound-guided foam sclerotherapy (UGFS), are becoming more popular. In a multicentre randomized controlled non-inferiority trial, the effectiveness and costs of UGFS and surgery for treatment of the incompetent great saphenous vein (GSV) were
B McAree et al.
European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery, 43(6), 721-725 (2012-04-18)
To compare the half-life of STD and polidocanol air-based foams and the damage they inflict upon human great saphenous vein in an in-vitro model. The time for the volume of 3% STD and polidocanol foams to reduce by 10% (T(90))
L Lund et al.
The Journal of urology, 191(5), 1347-1350 (2013-11-23)
We evaluate whether aspiration and sclerosing of hydrocele testis is an effective treatment. Men with symptomatic hydrocele testis were included in this prospective, double-blind, randomized study with polidocanol and placebo. Patients were randomized to active treatment or placebo at the
Alessandro Frullini et al.
Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 38(5), 741-747 (2012-05-01)
Foam sclerotherapy has been proven to be a safe and effective treatment for superficial venous insufficiency, but transient visual and neurologic disturbances continue to be reported. These side effects have been theorized to be related to the presence of air

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