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Merck

00990

Sigma-Aldrich

乙酰氯

puriss. p.a., ≥99.0% (T)

别名:

Acetic acid chloride, Acetic chloride, Ethanoyl chloride

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About This Item

线性分子式:
CH3COCl
CAS号:
分子量:
78.50
Beilstein:
605303
EC號碼:
MDL號碼:
分類程式碼代碼:
12352100
eCl@ss:
39050501
PubChem物質ID:
NACRES:
NA.21

蒸汽密度

2.7 (vs air)

品質等級

蒸汽壓力

11.69 psi ( 20 °C)
32.33 psi ( 55 °C)

等級

puriss. p.a.

化驗

≥99.0% (T)

形狀

liquid

自燃溫度

1353 °F

expl. lim.

19 %

折射率

n20/D 1.389 (lit.)
n20/D 1.389

bp

52 °C (lit.)

mp

−112 °C (lit.)

密度

1.104 g/mL at 25 °C (lit.)

正離子痕跡

Al: ≤0.5 mg/kg
Ba: ≤0.1 mg/kg
Bi: ≤0.1 mg/kg
Ca: ≤0.5 mg/kg
Cd: ≤0.05 mg/kg
Co: ≤0.02 mg/kg
Cr: ≤0.1 mg/kg
Cu: ≤0.02 mg/kg
Fe: ≤0.5 mg/kg
K: ≤0.5 mg/kg
Li: ≤0.1 mg/kg
Mg: ≤0.1 mg/kg
Mn: ≤0.02 mg/kg
Mo: ≤0.1 mg/kg
Na: ≤0.5 mg/kg
Ni: ≤0.02 mg/kg
Pb: ≤0.1 mg/kg
Sr: ≤0.1 mg/kg
Zn: ≤0.1 mg/kg

官能基

acyl chloride

SMILES 字串

CC(Cl)=O

InChI

1S/C2H3ClO/c1-2(3)4/h1H3

InChI 密鑰

WETWJCDKMRHUPV-UHFFFAOYSA-N

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一般說明

乙酰氯(酰氯)是用于酯化和Friedel-Crafts酰化反应的乙酰化试剂。

應用

乙酰氯可以用作:
  • 色谱-质谱联用(MS)降解聚氧乙二醇单烷基醚,测定乙氧基化程度的降解剂。
  • 用于羧酸酯化、N-boc脱保护和磷酰胺溶剂分解反应的含醇试剂。

象形圖

FlameCorrosion

訊號詞

Danger

危險聲明

危險分類

Eye Dam. 1 - Flam. Liq. 2 - Skin Corr. 1B

安全危害

儲存類別代碼

3 - Flammable liquids

水污染物質分類(WGK)

WGK 1

閃點(°F)

41.0 °F - closed cup

閃點(°C)

5 °C - closed cup

個人防護裝備

Faceshields, Gloves, Goggles


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A rapid and simple method for the esterification of fatty acids and steroid carboxylic acids prior to gas-liquid chromatography
Lillington JM, et al.
Clinica Chimica Acta; International Journal of Clinical Chemistry, 111(1), 91-98 (1981)
Comparisons of O-acylation and Friedel-Crafts acylation of phenols and acyl chlorides and Fries rearrangement of phenyl esters in trifluoromethanesulfonic acid: Effective synthesis of optically active homotyrosines
Murashige R, et al.
Tetrahedron, 67(3), 641-649 (2011)
Uta Ceglarek et al.
Metabolomics : Official journal of the Metabolomic Society, 12(12), 182-182 (2016-11-15)
Sensitive and specific assessment of the hepatic graft metabolism after liver transplantation (LTX) is essential for early detection of postoperative dysfunction implying the need for consecutive therapeutic interventions. Here, we assessed circulating liver metabolites of the cholesterol pathway, amino acids
Yu-Ting Liu et al.
The journal of physical chemistry. A, 114(27), 7275-7283 (2010-06-24)
In one-photon dissociation of gaseous acetyl chloride at 248 nm, time-resolved Fourier-transform infrared emission spectroscopy is used to detect the fragments of HCl, CO, and CH(2) in the presence of Ar or O(2). The high-resolution spectra of HCl and CO
Pavan K Kancharla et al.
The Journal of organic chemistry, 76(14), 5832-5837 (2011-05-27)
A new reagent system comprising acetyl chloride, silver nitrate, and acetonitrile has been developed for the synthesis of 2-nitroglycals from the corresponding glycals. Under certain conditions, the formation of 2-nitro-1-acetamido sugars has also been observed. In addition, a few other

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