等級
purum
品質等級
化驗
≥98.0% (GC)
bp
135 °C (lit.)
mp
59-61 °C
60-63 °C (lit.)
密度
0.901 g/mL at 25 °C (lit.)
SMILES 字串
C\C(C)=N/O
InChI
1S/C3H7NO/c1-3(2)4-5/h5H,1-2H3
InChI 密鑰
PXAJQJMDEXJWFB-UHFFFAOYSA-N
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訊號詞
Danger
危險分類
Acute Tox. 4 Dermal - Carc. 2 - Eye Dam. 1 - Flam. Sol. 2 - Skin Sens. 1B
儲存類別代碼
4.1B - Flammable solid hazardous materials
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
個人防護裝備
Eyeshields, Gloves, type N95 (US)
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The hepatocarcinogenicity of acetoxime has been tentatively linked with its metabolic oxidation to the potent genotoxicant and carcinogen propane 2-nitronate (P2-N). In order to test the hypothesis that acetoxime is metabolized to P2-N, the oxime (20 mM) was incubated with
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Previously, the secondary nitroalkane 2-nitropropane, a strong hepatocarcinogen in rats, had been shown to induce the formation of 8-aminoguanine in both DNA and RNA of rat liver through a sulfotransferase-mediated pathway. This pathway was postulated to convert the carcinogen into
Journal of the National Cancer Institute, 69(4), 961-962 (1982-10-01)
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Carcinogenesis, 21(2), 295-299 (2000-02-05)
The industrial solvent 2-nitropropane (2-NP) is a genotoxic hepatocarcinogen in rats. The genotoxicity of the compound in rats has been attributed to sulfotransferase-mediated formation of DNA-reactive nitrenium ions from the anionic form of 2-NP, propane 2-nitronate (P2N). Whether human sulfotransferases
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