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Merck
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Key Documents

0018-FP

Sigma-Aldrich

Neu5Gcα-C3-PAA-fluo

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About This Item

分類程式碼代碼:
12352201
NACRES:
NA.25

carrier

PAA carrier

標籤

FITC labeled

產品線

FP-Series

化驗

95% (H-NMR)

形狀

lyophilized powder

分子量

~20,000 Da

製造商/商標名

GlycoNZ

標籤範圍

1% Biotin per 20 mole % Poly[N-(2-hydroxyethyl)acrylamide-co-N-acrylamide] ligand density

技術

flow cytometry: suitable

probe type

monosaccharide

probe presentation

polymeric

儲存溫度

−20°C

一般說明

FP-Series: Fluorescein-Labeled Polymeric Probes
These glycoconjugate probes are designed to reveal lectins, including selectins, directly on cell membranes, organelles, and in cytoplasm. The low fluorescein content ensures that probe solubility in water is not affected, but still allows reliable probe detection. The affinity of the probes is 102 to 105 times higher than that of corresponding free sugars.

PAA is poly[N-(2-hydroxyethyl)acrylamide], a flexible polymer chain which serves as an additional spacer. Used as a molecular weight carrier, PAA demonstrates an absence of non-specific interaction with cells, and is stable to chemical and proteolytic action.

應用

Glycoconjugates are used to study the functions of carbohydrates, carbohydrate-binding proteins in biological processes, and on the discovery of new carbohydrate-mediated interactions.

準備報告

Purity: synthetic ω-aminoalkyl glycosides used for coupling with the polymer have a purity of >95% (HPLC and 1H-NMR)

儲存類別代碼

13 - Non Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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