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Key Documents

RKTX1MAG-37K

Millipore

MILLIPLEX® 大鼠肾毒性磁珠面板1-毒性多重测定

The analytes available for this multiplex kit are: Clusterin, GSTα, IP-10, KIM-1, OPN - Osteopontin, TIMP-1, VEGF.

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About This Item

分類程式碼代碼:
12161503
eCl@ss:
32161000
NACRES:
NA.84

品質等級

物種活性

rat

製造商/商標名

Milliplex®

assay range

accuracy: 70-123%
standard curve range: 0.03-20 ng/mL
(IP-10, KIM-1, OPN)

standard curve range: 0.03-20 ng/mL
(VEGF)

standard curve range: 0.27-200 ng/mL
(TIMP-1)

standard curve range: 2.06-1500 ng/mL
(Clusterin)

standard curve range: 4.12-3000 ng/mL
(GSTα)

inter-assay cv: <10%
intra-assay cv: <15%
(All other analytes)

inter-assay cv: <20%
intra-assay cv: <30%
(GSTα)

技術

multiplexing: suitable

檢測方法

fluorometric (Luminex xMAP)

運輸包裝

wet ice

一般說明

MILLIPLEX® 大鼠肾毒性磁珠面板1 & 2,加上微珠形式的Luminex® xMAP®平台,使您能够专注于发现,从而获得理想的速度和灵敏度优势,允许同时定量多重检测多种分析物,从而可以显著提高生产力。

面板类型:毒性

應用

  • 分析物:Clusterin GSTα IP-10 KIM-1 OPN - 骨桥蛋白TIMP-1 VEGF
  • 推荐的样品类型:尿液
  • 推荐的样品稀释度:1:2
  • 分析运行时间:过夜

特點和優勢

通过在此面板中选择可用的分析物来设计多重试剂盒。

其他說明

灵敏度:有关单个分析物的灵敏度,请参见试剂盒方案。

法律資訊

Luminex is a registered trademark of Luminex Corp
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp

象形圖

Skull and crossbonesEnvironment

訊號詞

Danger

危險分類

Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

標靶器官

Respiratory system

儲存類別代碼

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects


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Javad Habibi et al.
Cardiovascular diabetology, 18(1), 40-40 (2019-03-27)
Diabetic nephropathy (DN) is characterized by glomerular and tubulointerstitial injury, proteinuria and remodeling. Here we examined whether the combination of an inhibitor of neprilysin (sacubitril), a natriuretic peptide-degrading enzyme, and an angiotensin II type 1 receptor blocker (valsartan), suppresses renal
Kidney biomarkers in MCPA-induced acute kidney injury in rats: reduced clearance enhances early biomarker performance.
Wunnapuk, K; Liu, X; Gobe, GC; Endre, ZH; Peake, PW; Grice, JE; Roberts, MS; Buckley, NA
Toxicology Letters null
Iwan P Williams et al.
mAbs, 12(1), 1685349-1685349 (2019-11-27)
IgE monoclonal antibodies hold great potential for cancer therapy. Preclinical in vivo systems, particularly those in which the antibody recognizes the host species target antigen and binds to cognate Fc receptors, are often the closest approximation to human exposure and
Nadeeka S Udawatte et al.
Frontiers in pharmacology, 11, 511-511 (2020-05-12)
Candida albicans is the major fungal species associated with superficial mucosal infections such as oral candidiasis as well as systemic mycoses with high morbidity and mortality. On top of the rising drug resistance, currently available antifungal agents have significant adverse
Klintean Wunnapuk et al.
Toxicology letters, 225(1), 192-200 (2013-12-24)
Accidental or intentional ingestion of glyphosate surfactant-based herbicides, like Roundup(®), leads to nephrotoxicity as well as death. In this study, a panel of kidney injury biomarkers was evaluated in terms of suitability to detect acute kidney injury and dysfunction. The

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Multiplex toxicity assays enable researchers to simultaneously measure multiple toxicity biomarkers of various organs to gain a better understanding of toxicity. Explore how MILLIPLEX® multiplex toxicity assays are advancing research on liver injury, kidney toxicity, genotoxicity, and more.

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