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Merck
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Key Documents

MAB5520

Sigma-Aldrich

Anti-NG2 Chondroitin Sulfate Proteoglycan Antibody, clone 7.1

ascites fluid, clone 7.1, Chemicon®

别名:

NG2

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About This Item

分類程式碼代碼:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物源

mouse

品質等級

抗體表格

ascites fluid

抗體產品種類

primary antibodies

無性繁殖

7.1, monoclonal

物種活性

human

製造商/商標名

Chemicon®

技術

flow cytometry: suitable
western blot: suitable

同型

IgG1

NCBI登錄號

UniProt登錄號

運輸包裝

dry ice

目標翻譯後修改

unmodified

基因資訊

human ... CSPG4(1464)

特異性

NG2 (chondroitin sulfate proteoglycan), human which is the homologue of the rat NG2 molecule. The antibody reacts with a 220-240 kD surface protein whose N-terminal sequence is identical to the rat NG2 chondrotin sulfate proteoglycan molecule.

MAB5520 reacts with only neoplastic leukocytes with specific association with chromosome 11q23 translocations involving the MLL gene. It has a very high specificity for t(4;11) or t(11;19) translocations. The antibody shows no reactivity with normal marrow hematopoietic cells, peripheral blld leukocytes, red blood cells or platelets. Leukemic cells lines KG1, KG1a, HRL, Jurkat, K562, Raji, HL-60, U937, Daudi, Nalm6 and CEM are negative. However MAB5520 does react with a variety of cell lines of nonhematopoietic origin, including HeLa cells.

免疫原

Human bone marrow stromal cell line, SV40 transformed.

應用

Anti-NG2 Chondroitin Sulfate Proteoglycan Antibody, clone 7.1 is an antibody against NG2 Chondroitin Sulfate Proteoglycan for use in FC & WB.
Western blot

Flow cytometry

Optimal working dilutions must be determined by end user.

法律資訊

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

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儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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Benign mesenchymal stromal cells in human sarcomas.
Morozov, A; Downey, RJ; Healey, J; Moreira, AL; Lou, E; Franceschino, A; Dogan, Y; Leung et al.
Clinical cancer research : an official journal of the American Association for Cancer Research null

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