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Merck
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Key Documents

HPI-15K

Sigma-Aldrich

Human Proinsulin RIA

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About This Item

分類程式碼代碼:
12161503
eCl@ss:
32161000
NACRES:
NA.84

等級

for protein analysis

品質等級

描述

ED<sub>80</sub> = 10 ± 1 pM ED<sub>50</sub> = 23 ± 2 pM ED<sub>20</sub> = 52 ± 3 pM
analytes available: Proinsulin
2-100 pg/mL (standard curve range)

特點

accuracy 91–93%

物種活性

human

技術

radioimmunoassay: suitable

UniProt登錄號

檢測方法

radioactive

一般說明

FUNCTION: SwissProt: P01308 # Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
SIZE: 110 amino acids; 11981 Da
SUBUNIT: Heterodimer of a B chain and an A chain linked by two disulfide bonds.
SUBCELLULAR LOCATION: Secreted.
DISEASE:SwissProt: P01308 # Defects in INS are the cause of familial hyperproinsulinemia [MIM:176730].
SIMILARITY: SwissProt: P01308 ## Belongs to the insulin family.

應用

Three-day, disequilibrium incubation at room temperature. Sample volume ≤200 µL serum, plasma, or tissue culture media.

分析報告

Linearity 100–120%

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

訊號詞

Danger

危險分類

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Dam. 1 - STOT RE 2

標靶器官

Respiratory Tract

儲存類別代碼

10 - Combustible liquids


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