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Merck
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Key Documents

EZHFGF23

Millipore

Human FGF-23 ELISA Kit

measuress and quantifies FGF-23 levels in 50 μL serum, plasma or cell culture supernatent

别名:

ELISA Kit for Human FGF-23, FGF-23 ELISA, Human FGF-23 Detection

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About This Item

分類程式碼代碼:
12161503
eCl@ss:
32161000
NACRES:
NA.32

product name

Human FGF-23 ELISA Kit, This Human FGF-23 ELISA Kit is used to measure & quantify FGF-23 levels in Metabolism & Inflammation & Immunology research.

品質等級

物種活性

human

包裝

kit of 1 × 96 wells

參數

50 μL sample volume (4hr assay)

assay range

sensitivity: 9.9 pg/mL
(minimum detectable concentrations in tissue culture/serum/plasma)

standard curve range: 9.9-2400 pg/mL
inter-assay cv: <11%
intra-assay cv: <11%

技術

ELISA: suitable

輸入

sample type cell culture supernatant
sample type serum
sample type plasma (K2 EDTA)

應用

research use

檢測方法

colorimetric (450nm/590nm)

運輸包裝

wet ice

儲存溫度

2-8°C

一般說明

Studies demonstrate that Fibroblast Growth Hormone-23 plays a critical role as a phosphate-regulating hormone. FGF-23 is responsible for the inhibition of renal tubular reabsorption of inorganic phosphorus and, consequently, the regulation of phosphorus homeostasis. FGF-23 mRNA is expressed in the brain, in the thymus at low levels, in dendritic cells, with the highest expression in osteocytes and osteoblasts during phases of active bone remodeling. Because circulating levels of FGF-23 are regulated by vitamin D and phosphorus, normal skeletal and soft tissue development require vitamin D and a functional vitamin D signaling pathway. Diseases resulting from aberrant FGF-23 expression include inherited forms of rickets, certain kidney diseases and phosphorus-related tumors.

特異性

The antibody pair used in this assay cross-reacts 0.01% to Human FGF- 21 and 0.01% to FGF-19.

No significant cross-reactivity has been observed to other human and rat molecules/hormones tested

應用

50µl sample size, 2-Step assay with <4hr incubation time.
Research Category
Stem Cell Research
Used to detect/quantify: FGF-23

其他說明

Please contact Technical Service for linearity of dilution.

免責聲明

For research use only. Not for use in diagnostic procedures.

訊號詞

Danger

危險分類

Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Met. Corr. 1 - Skin Sens. 1

儲存類別代碼

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects


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