跳转至内容
Merck
所有图片(1)

文件

ABT1382

Sigma-Aldrich

Anti-Neurocan

from rabbit

别名:

Neurocan core protein, 245 kDa early postnatal core glycoprotein, Chondroitin sulfate proteoglycan 3

登录查看公司和协议定价


About This Item

分類程式碼代碼:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物源

rabbit

品質等級

抗體表格

unpurified

抗體產品種類

primary antibodies

無性繁殖

polyclonal

物種活性

rat

包裝

antibody small pack of 25 μL

技術

immunofluorescence: suitable

同型

IgG

UniProt登錄號

運輸包裝

ambient

目標翻譯後修改

unmodified

基因資訊

rat ... Ncan(58982)

一般說明

Neurocan core protein (UniProt: P55067; also known as 245 kDa early postnatal core glycoprotein, Chondroitin sulfate proteoglycan 3) is encoded by the Ncan (also known as Cspg3) gene in rat. Neurocan is a secreted protein of the aggrecan/versican proteoglycan family that is found in early postnatal and adult brain. During early postnatal development neurocan accounts for at least 20% of the protein of the soluble brain proteoglycans. Neurocan mostly contains chondroitin sulfate, but also has N-linked and O-linked oligosaccharides. It is shown to be involved in the modulation of cell adhesion and migration and regulates neurite outgrowth. Neurocan interact with several cell surface molecules, such as N-CAM, L1/Ng-CAM, etc., and modulates the cell-binding and neurite outgrowth promoting activates of these molecules. Neurocan is synthesized with a 22 aa signal peptide that is subsequently cleaved to produce the mature form. Neurocan contains one C-type lectin domain, two EGF-like domains, one Ig-like V type domain, two link domains and one Sushi (CCP/SCR) domain. (Ref.: Rauch, U., et al. (2001) Cell Mol. Life Sci. 58(12-13):1842-56; Zhou, XH et al. (2001). Mol. Cell Biol. 21(17): 5970-78).

特異性

This rabbit polyclonal antibody detects Neurocan in fetal and adult rat brain.

免疫原

Epitope: unknown
Full-length Neurocan isolated from 7-day embryonic rat brain and purified by monoclonal antibody immunoaffinity chromatography.

應用

Research Category
Cell Structure
This rabbit polyclonal Anti-Neurocan, Cat. No. ABT1382, is a rabbit polyclonal antibody that detects Neurocan core protein and has been tested for use in Immunofluorescence.

品質

Evaluated by Immunofluorescence in E14 embryonic rat brain (frozen sections) and adult rat brain (frozen sections).

Immunofluorescence Analysis: A 1:500 dilution of this antibody detected Neurocan in E14 embryonic rat brain (frozen sections) and rat E14 neocortex.

標靶描述

135.55 kDa calculated.

外觀

Unpurified
Format: Unpurified
Rabbit polyclonal antiserum with 0.05% sodium azide.

儲存和穩定性

Stable for 1 year at -20°C from date of receipt.

Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.

其他說明

Concentration: Please refer to lot specific datasheet.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Not finding the right product?  

Try our 产品选型工具.

儲存類別代碼

12 - Non Combustible Liquids

水污染物質分類(WGK)

WGK 1


分析证书(COA)

输入产品批号来搜索 分析证书(COA) 。批号可以在产品标签上"批“ (Lot或Batch)字后找到。

已有该产品?

在文件库中查找您最近购买产品的文档。

访问文档库

Guo-Yu Wang et al.
Neural regeneration research, 16(8), 1638-1644 (2021-01-13)
Cell transplantation is a potential treatment for spinal cord injury. Olfactory ensheathing cells (OECs) play an active role in the repair of spinal cord injury as a result of the dual characteristics of astrocytes and Schwann cells. However, the specific

我们的科学家团队拥有各种研究领域经验,包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系技术服务部门