ABN467

Anti-CX3CL1 Antibody

from rabbit, purified by affinity chromatography

• 别名: Fractalkine, C-X3-C motif chemokine 1, CX3C membrane-anchored chemokine, Neurotactin, Small-inducible cytokine D1, FKN, NTT, SCYD1, A-152E5.2
• 分類程式碼代碼: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

属性

• 生物源: rabbit
• 品質等級: 100
• 抗體表格: affinity isolated antibody
• 抗體產品種類: primary antibodies
• 無性繁殖: polyclonal
• 純化經由: affinity chromatography
• 物種活性: mouse
• 物種活性（以同源性預測）: human (immunogen homology)
• 技術: western blot: suitable
• UniProt登錄號: P78423
• 運輸包裝: wet ice
• 目標翻譯後修改: unmodified
• 基因資訊: mouse ... Cx3Cl1(20312)

说明

一般說明

C-X3-C motif chemokine 1 (CX3CL1), also known as CX3C membrane-anchored chemokine, Neurotactin (NTT), Small-inducible cytokine D1 (SCYD1), and Fractalkine (FKN), is a CX3C chemokine known to induce adhesion and migration of leukocytes. Recent studies have shown that CX3CL1 can suppress the production of nitrous oxide, interleukin-6, and TNF-alpha in activated microglia and neuronal cells, and it may act as an intrinsic inhibitor against neurotoxicity by activated microglia. Other evidence suggests that CX3CL1 may play a role in regulating leukocyte adhesion and migration processes at the endothelium. Additionally, CX3CL1 is implied to inhibit CX3CR1, which is a co-receptor for HIV-1 and HIV-2 envelope fusion and virus infection. CX3CL1 is expressed in small intestine, colon, testis, prostate, heart, brain, lung, skeletal muscle, kidney and pancreas.

免疫原

KLH-conjugated linear peptide corresponding to human CX3CL1.

應用

Anti-CX3CL1 Antibody is a highly specific rabbit polyclonal antibody, that targets CX3CL1 & has been tested in western blotting.

Research Category
Neuroscience

Research Sub Category
Developmental Neuroscience

品質

Evaluated by Western Blotting in C2C12 cell lysate.

Western Blotting Analysis: 2 µg/mL of this antibody detected CX3CL1 in 15 µg of C2C12 cell lysate.

標靶描述

~50 kDa observed.

外觀

Antigen Affinity Purified

Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.

儲存和穩定性

Stable for 1 year at 2-8°C from date of receipt.

分析報告

Control
C2C12 cell lysate

其他說明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全信息

• 儲存類別代碼: 10 - Combustible liquids
• 水污染物質分類（WGK）: WGK 2
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable