ABF199

Anti-TIM-1 Antibody

from rabbit, purified by affinity chromatography

• 别名: Hepatitis A virus cellular receptor 1, HAVcr-1, Kidney injury molecule 1, KIM-1, T-cell immunoglobulin and mucin domain-containing protein 1, TIMD-1, T-cell membrane protein 1, TIM-1, TIM, KIM1, TIM1, TIMD1
• 分類程式碼代碼: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

属性

• 生物源: rabbit
• 品質等級: 100
• 抗體表格: affinity isolated antibody
• 抗體產品種類: primary antibodies
• 無性繁殖: polyclonal
• 純化經由: affinity chromatography
• 物種活性: human
• 技術: immunofluorescence: suitable; immunohistochemistry: suitable; western blot: suitable
• UniProt登錄號: Q96D42
• 運輸包裝: wet ice
• 目標翻譯後修改: unmodified
• 基因資訊: human ... HAVCR1(26762)

说明

一般說明

T-cell immunoglobulin and mucin domain-containing protein 1 (TIMD-1, TIM-1, TIM, TIM1, TIMD1), also known as Hepatitis A virus cellular receptor 1 (HAVcr-1) and Kidney injury molecule 1(KIM-1, KIM1), may play an important role in T-helper cell development and the regulation of asthma and allergic diseases. In the case of human hepatitis A virus (HHAV) infection, TIM-1 functions as a cell-surface receptor for the virus, through which the hepatitis A virus can gain entry into a cell. Additional evidence implies that it may play a role in kidney injury and repair. TIM-1 is widely expressed, with highest levels in kidney and testis. It is also expressed by activated CD4+ T-cells during the development of helper T-cells responses. Furthermore, TIM-1 is expressed on T helper 2 (Th2) cells of the immune system, and following the binding of its natural ligand TIM-4, stimulates T cell expansion and cytokine production in response to viral challenge.

特異性

This antibody recognizes the N-terminus of TIM-1.

免疫原

Epitope: N-terminus

KLH-conjugated linear peptide corresponding to the N-terminus of human TIM-1.

應用

Anti-TIM-1 Antibody is a highly specific rabbit polyclonal antibody, that targets T-cell immunoglobulin & mucin domain-containing protein 1 & has been tested in western blotting, IHC & Immunofluorescence.

Immunohistochemistry Analysis: 10 µg/mL from a representative lot detected TIM-1 in human uterus tissue.

Immunofluorescence Analysis: 20 µg/mL from a representative lot detected TIM-1 in human uterus tissue.

Research Category
Inflammation & Immunology

Research Sub Category
Immunoglobulins & Immunology

品質

Evaluated by Western Blotting in human uterus tissue lysate.

Western Blotting Analysis: 1 µg/mL of this antibody detected TIM-1 in 15 µg of human uterus tissue lysate.

標靶描述

~48 kDa observed. Uncharacterized bands may appear in some lysate(s).

外觀

Antigen Affinity Purified

Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.

儲存和穩定性

Stable for 1 year at 2-8°C from date of receipt.

分析報告

Control
Human uterus tissue lysate

其他說明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全信息

• 儲存類別代碼: 12 - Non Combustible Liquids
• 水污染物質分類（WGK）: WGK 2
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable