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Merck
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Key Documents

ABE81

Sigma-Aldrich

Anti-NXF1 Antibody

serum, from rabbit

别名:

Nuclear RNA export factor 1, Tip-associated protein, Tip-associating protein, mRNA export factor TAP

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About This Item

分類程式碼代碼:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物源

rabbit

品質等級

抗體表格

serum

抗體產品種類

primary antibodies

無性繁殖

polyclonal

物種活性

mouse, rat, human

技術

western blot: suitable

NCBI登錄號

UniProt登錄號

運輸包裝

wet ice

目標翻譯後修改

unmodified

基因資訊

human ... NXF1(10482)

一般說明

Nuclear RNA export factor 1 (also known as Tap protein) is encoded by the NXF1 gene. The protein expressed by this gene is one member of a family of nuclear RNA export factor gene. The Nuclear RNA export factor 1 protein is involved in export of mRNA species bearing retroviral constitutive transport elements (CTE) from the nucleus as well as in the export of mRNA from the nucleus to the cytoplasm. This protein is localized predominantly in the nucleoplasm at both the nucleoplasmic and cytoplasmic faces of the nuclear pore complex. However, this protein shuttles between the nucleus and the cytoplasm and binds in vivo to poly(A) RNA. This protein is present in the nuclear Y14 complex and has been shown to interact with Aly/REF.

免疫原

Recombinant protein corresponding to human NXF1.

應用

Research Category
Epigenetics & Nuclear Function
Research Sub Category
RNA Metabolism & Binding Proteins
Use Anti-NXF1 Antibody (Rabbit Polyclonal Antibody) validated in WB to detect NXF1 also known as Nuclear RNA export factor 1, Tip-associated protein.

品質

Evaluated by Western Blot in A431 cell lysate.

Western Blot Analysis: A 1:1,000 dilution of this antibody detected NXF1 on 10 µg of A431 cell lysate.

標靶描述

~72 kDa observed. Two isoforms at 70 and 40 kDa have been described. Uncharacterized bands at ~48 and 100 kDa have been observed in some lysates.

外觀

Unpurified
Rabbit polyclonal serum containing 0.05% sodium azide.

儲存和穩定性

Stable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.

分析報告

Control
A431 cell lysate

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 1


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