ABC841

Anti-Caspase-14 Antibody

from rabbit, purified by affinity chromatography

• 别名: Caspase-14, CASP-14
• 分類程式碼代碼: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

属性

• 生物源: rabbit
• 品質等級: 100
• 抗體表格: affinity isolated antibody
• 抗體產品種類: primary antibodies
• 無性繁殖: polyclonal
• 純化經由: affinity chromatography
• 物種活性: human
• 技術: immunohistochemistry: suitable; western blot: suitable
• UniProt登錄號: P31944
• 運輸包裝: wet ice
• 目標翻譯後修改: unmodified
• 基因資訊: human ... CASP14(23581)

说明

一般說明

Caspases are a family of cysteine proteases that can be divided into apoptotic and inflammatory caspase subfamilies. Caspase-14 exists as 2 subunits (p19 and p10) and is highly expressed in embryonic but not adult tissues. It is processed and activated by caspase 8 and caspase 10 in vitro, and by anti-Fas agonist antibody or TNF-related apoptosis inducing ligand in vivo. The expression and processing of this caspase may be involved in the keratinocyte terminal differentiation, which is important for the formation of the skin barrier.

特異性

This antibody detects the pro-form of Caspase-14 as well as the large subunit cleaved form.

免疫原

KLH-conjugated linear peptide corresponding to 16 amino acids near the C-terminus of human Caspase-14.

應用

Anti-Caspase-14 Antibody is a highly specific rabbit polyclonal antibody, that targets Caspase 14 & has been tested in western blotting & IHC.

Immunohistochemistry Analysis: 2.5 μg/mL from a representative lot detected Caspase-14 in human liver tissue.

品質

Evaluated by Western Blotting in Jurkat cell lysate with and without blocking peptide.

Western Blotting Analysis: 1 μg/mL of this antibody detected Caspase-14 in Jurkat cell lysate with and without blocking peptide.

標靶描述

~28 kDa observed. Uncharacterized bands may be observed in some lysate(s).

其他說明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

安全信息

• 儲存類別代碼: 12 - Non Combustible Liquids
• 水污染物質分類（WGK）: WGK 2
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable