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Merck
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主要文件

AB5986P

Sigma-Aldrich

Anti-Tyrosine Hydroxylase Antibody

CHEMICON®, rabbit polyclonal

别名:

TH, Tyrosine Monooxygenase

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About This Item

分類程式碼代碼:
12352203
eCl@ss:
32160702
NACRES:
NA.41

product name

Anti-Tyrosine Hydroxylase Antibody, Chemicon®, from rabbit

生物源

rabbit

品質等級

抗體表格

affinity purified immunoglobulin

抗體產品種類

primary antibodies

無性繁殖

polyclonal

純化經由

affinity chromatography

物種活性

rat

製造商/商標名

Chemicon®

技術

immunohistochemistry: suitable

UniProt登錄號

運輸包裝

dry ice

目標翻譯後修改

unmodified

基因資訊

human ... TH(7054)

特異性

Tyrosine Hydroxylase. Immunohistochemical distribution throughout the brain shows that staining is restricted to those neurons known to contain the enzyme. The antibody has proven useful in staining catecholaminergic neurons. AB5986 stains these neurons intensely, including dendritic processes and fine nerve terminals.

免疫原

Synthetic peptide corresponding to amino acids 32-47 of rat Tyrosine Hydroxylase.

應用

Detect Tyrosine Hydroxylase using this Anti-Tyrosine Hydroxylase Antibody validated for use in IH.
Immunohistochemistry: 0.5-1.0 μg/mL.

Optimal working dilutions must be determined by end user.
Research Category
Neuroscience
Research Sub Category
Neurotransmitters & Receptors

Neuronal & Glial Markers

外觀

Affinity purified immunoglobulin.

法律資訊

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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D Rotllant et al.
Neuroscience, 168(3), 691-705 (2010-04-22)
Previous studies have shown that amphetamine (AMPH) markedly activates dopaminergic projection areas, together with some important limbic nuclei. However, a global picture of the brain areas activated is lacking and the contribution of the dose of the drug and individual
Immunohistochemical studies on phosphorylation of tyrosine hydroxylase in central catecholamine neurons using site- and phosphorylation state-specific antibodies.
Xu, Z Q, et al.
Neuroscience, 82, 727-738 (1998)
Stephanie J Cragg et al.
The European journal of neuroscience, 20(7), 1788-1802 (2004-09-24)
The direct modulation of subthalamic nucleus (STN) neurons by dopamine (DA) neurons of the substantia nigra (SN) is controversial owing to the thick caliber and low density of DA axons in the STN. The abnormal activity of the STN in
Antibodies to a segment of tyrosine hydroxylase phosphorylated at serine 40.
Goldstein, M, et al.
Journal of Neurochemistry, 64, 2281-2287 (1995)
Antibodies to a synthetic peptide corresponding to a Ser-40-containing segment of tyrosine hydroxylase: activation and immunohistochemical localization of tyrosine hydroxylase.
Lee, K Y, et al.
Journal of Neurochemistry, 53, 1238-1244 (1989)

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